Ole Hyldegaard

Publikation

Publikationer pr. år 2008 2016 2017 2018 2019 2020

• 39 Tidsskriftartikel
• 1 Konferenceartikel

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2020

  Effect of progressive resistance training on persistent pain after axillary dissection in breast cancer: a randomized controlled trial

  Ammitzbøll, G., Andersen, K. G., Bidstrup, P. E., Johansen, C., Lanng, C., Kroman, N., Zerahn, B., Hyldegaard, O., Andersen, E. W. & Dalton, S. O., 1 jan. 2020, I: Breast Cancer Research and Treatment.

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  • Resistance Training 100%
  • Dissection 77%
  • Randomized Controlled Trials 60%
  • Breast Neoplasms 57%
  • Pain 51%
  1 Citationer (Scopus)
• 2019

  A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: A replicated, randomized controlled clinical trial

  Wahl, A. M., Bidstrup, D., Smidt-Nielsen, I. G., Werner, M. U., Hyldegaard, O. & Rotbøll-Nielsen, P., 2019, I: Journal of Pain Research. 12, s. 2337-2348

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  • Hyperbaric Oxygenation 100%
  • Neuronal Plasticity 74%
  • Randomized Controlled Trials 52%
  • Hyperalgesia 45%
  • Wounds and Injuries 14%
  1 Citationer (Scopus)

  2 Downloads (Pure)

• Biofilm in group A streptococcal necrotizing soft tissue infections

  Siemens, N., Chakrakodi, B., Shambat, S. M., Morgan, M., Bergsten, H., Hyldegaard, O., Skrede, S., Arnell, P., Madsen, M. B., Johansson, L., INFECT Study Group, Juarez, J., Bosnjak, L., Mörgelin, M., Svensson, M. & Norrby-Teglund, A., 7 jul. 2019, I: JCI insight. 1, 10, e87882.

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  • Soft Tissue Infections 100%
  • Biofilms 80%
  • Streptococcus 72%
  • Infections 22%
  • Necrotizing Fasciitis 15%
  29 Citationer (Scopus)

• Group A Streptococcal DNase Sda1 Impairs Plasmacytoid Dendritic Cells' Type 1 Interferon Response

  Keller, N., Woytschak, J., Heeb, L. E. M., Marques Maggio, E., Mairpady Shambat, S., Snäll, J., Hyldegaard, O., Boyman, O., Norrby-Teglund, A. & Zinkernagel, A. S., jun. 2019, I: The Journal of Investigative Dermatology. 139, 6, s. 1284-1293

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  • Virulence Factor 100%
  • Deoxyribonucleases 90%
  • Dendritic Cells 64%
  • Necrotizing Fasciitis 64%
  • Virulence Factors 50%
  3 Citationer (Scopus)

• Patient’s characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study

  Madsen, M. B., Skrede, S., Perner, A., Arnell, P., Nekludov, M., Bruun, T., Karlsson, Y., Hansen, M. B., Polzik, P., Hedetoft, M., Rosén, A., Saccenti, E., Bergey, F., Martins dos Santos, V. A. P., INFECT Study Group, Norrby-Teglund, A. & Hyldegaard, O., 2019, I: Intensive Care Medicine. 45, s. 1241-1251 11 s.

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  • Soft Tissue Infections 100%
  • Cohort Studies 56%
  • Prospective Studies 52%
  • Mortality 29%
  • Streptococcus 25%
  27 Citationer (Scopus)

• Progressive resistance training to prevent arm lymphedema in the first year after breast cancer surgery: Results of a randomized controlled trial

  Ammitzbøll, G., Johansen, C., Lanng, C., Andersen, E. W., Kroman, N., Zerahn, B., Hyldegaard, O., Wittenkamp, M. C. & Dalton, S. O., 2019, I: Cancer. 125, 10, s. 1683-1692 10 s.

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  • Lymphedema 100%
  • Resistance Training 93%
  • Randomized Controlled Trials 56%
  • Breast Neoplasms 53%
  • Exercise 21%
  15 Citationer (Scopus)

• SuPAR correlates with mortality and clinical severity in patients with necrotizing soft-tissue infections: results from a prospective, observational cohort study

  Polzik, P., Grøndal, O., Tavenier, J., Madsen, M. B., Andersen, O., Hedetoft, M. & Hyldegaard, O., 1 dec. 2019, I: Scientific Reports. 9, 8 s., 5098.

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  • Urokinase Plasminogen Activator Receptors 100%
  • Soft Tissue Infections 86%
  • Observational Studies 55%
  • Cohort Studies 48%
  • Organ Dysfunction Scores 41%
  5 Citationer (Scopus)

  10 Downloads (Pure)

• The clinical use of hyperbaric oxygen in the treatment of Danish patients with diabetic foot ulcers

  Vinkel, J., Lohse, N. & Hyldegaard, O., feb. 2019, I: Danish Medical Journal. 66, 2, 6 s., A5528.

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  • Diabetic Foot 100%
  • Hyperbaric Oxygenation 59%
  • Oxygen 59%
  • Amputation 27%
  • Comorbidity 14%
  1 Citationer (Scopus)

  9 Downloads (Pure)
• 2018

  Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine With Morbidity and Mortality in Patients With Necrotizing Soft Tissue Infections

  Hansen, M. B., Rasmussen, L. S., Garred, P., Pilely, K., Wahl, A. M., Perner, A., Madsen, M. B., Hedegaard, E. R., Simonsen, U. & Hyldegaard, O., 1 jun. 2018, I: Shock. 49, 6, s. 667-674

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  • N,N-dimethylarginine 100%
  • Soft Tissue Infections 87%
  • Nitrites 78%
  • Arginine 66%
  • Morbidity 42%
  4 Citationer (Scopus)

  43 Downloads (Pure)

• Diabetes and necrotizing soft tissue infections - A prospective observational cohort study: Statistical analysis plan

  Rosén, A., Arnell, P., Madsen, M. B., Nedrebø, B. G., Norrby-Teglund, A., Hyldegaard, O., Dos Santos, V. M., Bergey, F., Saccenti, E., INFECT Study Group & Skrede, S., sep. 2018, I: Acta Anaesthesiologica Scandinavica. 62, 8, s. 1171-1177

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  • Soft Tissue Infections 100%
  • Observational Studies 64%
  • Cohort Studies 56%
  • Mortality 17%
  • Simplified Acute Physiology Score 16%
  2 Citationer (Scopus)

• Forensic Case Reports Presenting Immersion Pulmonary Edema as a Differential Diagnosis in Fatal Diving Accidents

  Vinkel, J., Bak, P., Juel Thiis Knudsen, P. & Hyldegaard, O., 2018, I: Journal of Forensic Sciences. 63, 1, s. 299-304 6 s.

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  • Diving 100%
  • Immersion 83%
  • Pulmonary Edema 81%
  • Accidents 69%
  • Differential Diagnosis 58%
  3 Citationer (Scopus)

• Immunoregulation of Neutrophil Extracellular Trap Formation by Endothelial-Derived p33 (gC1q Receptor)

  Neumann, A., Papareddy, P., Westman, J., Hyldegaard, O., Snäll, J., Norrby-Teglund, A. & Herwald, H., 1 feb. 2018, I: Journal of Innate Immunity. 10, 1, s. 30-43

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  • Alarmins 100%
  • Extracellular Traps 93%
  • Peroxidase 63%
  • Streptococcus pyogenes 40%
  • Bacteria 22%
  7 Citationer (Scopus)

• Necrotizing soft tissue infections - a multicentre, prospective observational study (INFECT): protocol and statistical analysis plan

  Madsen, M. B., Skrede, S., Bruun, T., Arnell, P., Rosén, A., Nekludov, M., Karlsson, Y., Bergey, F., Saccenti, E., Martins dos Santos, V. A. P., Perner, A., Norrby-Teglund, A. & Hyldegaard, O., 1 feb. 2018, I: Acta Anaesthesiologica Scandinavica. 62, 2, s. 272-279

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  • Soft Tissue Infections 100%
  • Observational Studies 64%
  • Prospective Studies 52%
  • Necrotizing Fasciitis 31%
  • Mortality 29%
  14 Citationer (Scopus)

• Neuronal nitric oxide inhibition attenuates the protective effect of HBO2 during cyanide poisoning

  Hedetoft, M., Polzik, P., Olsen, N. V. & Hyldegaard, O., 1 maj 2018, I: Undersea & Hyperbaric Medicine. 45, 3, s. 335-350

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  • 7-nitroindazole 100%
  • Cyanides 86%
  • Poisoning 67%
  • Nitric Oxide 53%
  • Glycerol 27%
  1 Citationer (Scopus)

• Pivotal Role of Preexisting Pathogen-Specific Antibodies in the Development of Necrotizing Soft-Tissue Infections

  INFECT Study Group, 5 jun. 2018, I: The Journal of Infectious Diseases. 218, s. 44-52

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  • Soft Tissue Infections 100%
  • Intravenous Immunoglobulins 55%
  • Antibodies 45%
  • Streptococcus pyogenes 40%
  • Infections 31%
  6 Citationer (Scopus)

• Protein SIC secreted from Streptococcus pyogenes forms complexes with extracellular histones that boost cytokine production

  Westman, J., Chakrakodi, B., Snäll, J., Mörgelin, M., Madsen, M. B., Hyldegaard, O., Neumann, A., Frick, I. M., Norrby-Teglund, A., Björck, L. & Herwald, H., 2018, I: Frontiers in Immunology. 9, 14 s., 236.

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  • Streptococcus pyogenes 100%
  • Histones 76%
  • Cytokines 50%
  • Proteins 30%
  • Complement Inactivating Agents 17%
  10 Citationer (Scopus)

  41 Downloads (Pure)
• 2017

  Association between cytokine response, the LRINEC score and outcome in patients with necrotising soft tissue infection: a multicentre, prospective study

  Hansen, M. B., Rasmussen, L. S., Svensson, M., Chakrakodi, B., Bruun, T., Madsen, M. B., Perner, A., Garred, P., Hyldegaard, O., Norrby-Teglund, A. & INFECT Study Group, 8 feb. 2017, I: Scientific Reports. 7, 12 s., 42179.

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  • Necrotizing Fasciitis 100%
  • Soft Tissue Infections 91%
  • Interleukin-1 74%
  • Multicenter Studies 65%
  • Interleukin-6 57%
  21 Citationer (Scopus)

  52 Downloads (Pure)

• How biomarkers reflect the prognosis and treatment of necrotising soft tissue infections and the effects of hyperbaric oxygen therapy: the protocol of the prospective cohort PROTREAT study conducted at a tertiary hospital in Copenhagen, Denmark

  Polzik, P., Johansson, P. I. & Hyldegaard, O., 1 okt. 2017, I: B M J Open. 7, 10, 8 s., e017805.

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  • Hyperbaric Oxygenation 100%
  • Soft Tissue Infections 94%
  • Urokinase Plasminogen Activator Receptors 86%
  • Denmark 82%
  • Tertiary Care Centers 68%
  4 Citationer (Scopus)

  10 Downloads (Pure)

• Hyperbaric oxygen therapy may overcome nitric oxide blockage during cyanide intoxication

  Polzik, P., Hansen, M. B., Olsen, N. V., Grondal, O. & Hyldegaard, O., 1 maj 2017, I: Undersea & Hyperbaric Medicine. 44, 3, s. 221-234

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  • Cyanides 100%
  • Hyperbaric Oxygenation 98%
  • Nitric Oxide 62%
  • NG-Nitroarginine Methyl Ester 58%
  • Lactic Acid 57%
  1 Citationer (Scopus)

• Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis

  Lerche, C. J., Christophersen, L. J., Kolpen, M., Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, O., Bundgaard, H., Jensen, P. Ø., Høiby, N. & Moser, C., sep. 2017, I: International Journal of Antimicrobial Agents. 50, 3, s. 406-412

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  • Hyperbaric Oxygenation 100%
  • Tobramycin 97%
  • Endocarditis 80%
  • Staphylococcus aureus 66%
  • Oxygen 55%
  15 Citationer (Scopus)

• Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial

  Madsen, M. B., Hjortrup, P. B., Hansen, M. B., Lange, T., Norrby-Teglund, A., Hyldegaard, O. & Perner, A., 1 nov. 2017, I: Intensive Care Medicine. 43, 11, s. 1585-1593 9 s.

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  • Soft Tissue Infections 100%
  • Intravenous Immunoglobulins 92%
  • Immunoglobulin G 62%
  • Placebos 56%
  • Random Allocation 30%
  43 Citationer (Scopus)

• Progressive strength training to prevent LYmphoedema in the first year after breast CAncer: the LYCA feasibility study

  Ammitzbøll, G., Lanng, C., Kroman, N., Zerahn, B., Hyldegaard, O., Kaae Andersen, K., Johansen, C. & Dalton, S. O., 1 feb. 2017, I: Acta Oncologica. 56, 2, s. 360-366

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  • Lymphedema 100%
  • Resistance Training 93%
  • Feasibility Studies 86%
  • Exercise 54%
  • Breast Neoplasms 53%
  16 Citationer (Scopus)

• Quantitative Romberg's test in acute carbon monoxide poisoning treated by hyperbaric oxygen

  Bidstrup, D., Jansen, E. C. & Hyldegaard, O., 1 nov. 2017, I: Undersea & Hyperbaric Medicine. 44, 6, s. 559-567

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  • Carbon Monoxide Poisoning 100%
  • Carbon Monoxide 57%
  • Oxygen 50%
  • Linear Models 22%
  • Hyperbaric Oxygenation 18%
  2 Citationer (Scopus)

• Treatment with 24 h-delayed normo- and hyperbaric oxygenation in severe sepsis induced by cecal ligation and puncture in rats

  Bærnthsen, N. F., Hansen, M. B., Wahl, A. M., Simonsen, U. & Hyldegaard, O., 25 nov. 2017, I: Journal of Inflammation. 14, 9 s., 27.

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  • Hyperbaric Oxygenation 100%
  • Punctures 76%
  • Ligation 68%
  • Sepsis 62%
  • Interleukin-6 59%
  2 Citationer (Scopus)

  46 Downloads (Pure)
• 2016

  Danish diving-related fatalities 1999-2012

  Vinkel, J., Bak, P. & Hyldegaard, O., 1 sep. 2016, I: Diving and Hyperbaric Medicine. 46, 3, s. 142-149 8 s.

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  • Diving 100%
  • empirics 49%
  • cause of death 42%
  • water 29%
  • police 28%
  8 Citationer (Scopus)

• Decompression illness treated in Denmark 1999-2013

  Juhl, C. S., Hedetoft, M., Bidstrup, D., Jansen, E. C. & Hyldegaard, O., 1 jun. 2016, I: Diving and Hyperbaric Medicine. 46, 2, s. 87-91 5 s.

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  • Denmark 100%
  • Decompression 94%
  • illness 75%
  • Diving 41%
  • Weights and Measures 29%
  1 Citationer (Scopus)

• Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse

  Chella Krishnan, K., Mukundan, S., Alagarsamy, J., Hur, J., Nookala, S., Siemens, N., Svensson, M., Hyldegaard, O., Norrby-Teglund, A. & Kotb, M., jul. 2016, I: P L o S Pathogens. 12, 7, e1005732.

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  • Soft Tissue Infections 100%
  • mice 47%
  • Genetic Loci 44%
  • infection 43%
  • quantitative genetics 39%
  16 Citationer (Scopus)

• Pentraxin-3 as a marker of disease severity and risk of death in patients with necrotizing soft tissue infections: a nationwide, prospective, observational study

  Hansen, M. B., Rasmussen, L. S., Garred, P., Bidstrup, D., Madsen, M. B. & Hyldegaard, O., 15 feb. 2016, I: Critical Care. 20, 11 s., 40.

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  • PTX3 protein 100%
  • Soft Tissue Infections 79%
  • Observational Studies 51%
  • Prospective Studies 41%
  • Septic Shock 33%
  23 Citationer (Scopus)

• The Lectin Complement Pathway in Patients with Necrotizing Soft Tissue Infection

  Hansen, M. B., Rasmussen, L. S., Pilely, K., Hellemann, D., Hein, E., Madsen, M. B., Hyldegaard, O. & Garred, P., 1 aug. 2016, I: Journal of Innate Immunity. 8, 5, s. 507-16 10 s.

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  • ficolin 100%
  • Mannose-Binding Lectin Complement Pathway 98%
  • Soft Tissue Infections 74%
  • Mannose-Binding Lectin 24%
  • Mortality 21%
  12 Citationer (Scopus)
• 2015

  Biomarkers of necrotising soft tissue infections: aspects of the innate immune response and effects of hyperbaric oxygenation-the protocol of the prospective cohort BIONEC study

  Hansen, M. B., Simonsen, U., Garred, P. & Hyldegaard, O., 2015, I: B M J Open. 5, 5, s. 1-9 9 s., e006995.

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  • Hyperbaric Oxygenation 100%
  • Soft Tissue Infections 94%
  • Innate Immunity 71%
  • Cohort Studies 53%
  • Biomarkers 50%
  8 Citationer (Scopus)

• Effect of nitric oxide on spinal evoked potentials and survival rate in rats with decompression sickness

  Randsøe, T., Meehan, C. F., Broholm, H. & Hyldegaard, O., 1 jan. 2015, I: Journal of Applied Physiology. 118, 1, s. 20-8 9 s.

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  • Decompression Sickness 100%
  • isosorbide-5-mononitrate 83%
  • Glycerol 71%
  • Evoked Potentials 65%
  • Nitric Oxide 54%
  1 Citationer (Scopus)

• Postural stability in patients with decompression sickness evaluated by means of Quantitative Romberg testing

  Hedetoft, M. & Hyldegaard, O., 1 sep. 2015, I: Undersea & Hyperbaric Medicine. 42, 5, s. 389-98 10 s.

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  • Decompression Sickness 100%
  • Vertigo 50%
  • Hyperbaric Oxygenation 14%
  • Reference Values 8%
  • Datasets 8%
  1 Citationer (Scopus)
• 2014

  Cerebral proton magnetic resonance spectroscopy demonstrates reversibility of N-acetylaspartate/creatine in gray matter after delayed encephalopathy due to carbon monoxide intoxication: a case report

  Hansen, M. B., Kondziella, D., Danielsen, E. R., Larsen, V. A., Jansen, E. C. & Hyldegaard, O., 19 jun. 2014, I: Journal of Medical Case Reports. 8, s. 1-5 5 s., 211.

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  • N-acetylaspartate 100%
  • Creatine 91%
  • Proton Magnetic Resonance Spectroscopy 90%
  • Carbon Monoxide 79%
  • Gray Matter 78%
  3 Citationer (Scopus)

• Treatment of micro air bubbles in rat adipose tissue at 25 kPa altitude exposures with perfluorocarbon emulsions and nitric oxide

  Randsøe, T. & Hyldegaard, O., jan. 2014, I: European Journal of Applied Physiology. 114, 1, s. 135-146 12 s.

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  • Fluorocarbons 100%
  • Emulsions 78%
  • Adipose Tissue 60%
  • Nitric Oxide 58%
  • Air 57%
  1 Citationer (Scopus)
• 2013

  Combined administration of hyperbaric oxygen and hydroxocobalamin improves cerebral metabolism after acute cyanide poisoning in rats

  Hansen, M. B., Olsen, N. V. & Hyldegaard, O., 1 nov. 2013, I: Journal of Applied Physiology. 115, 9, s. 1254-1261 8 s.

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  • Hydroxocobalamin 100%
  • Cyanides 80%
  • Hyperbaric Oxygenation 79%
  • Poisoning 62%
  • Oxygen 44%
  4 Citationer (Scopus)

• Diagnostic and Prognostic Impact of Circulating YKL-40, IL-6, and CA 19.9 in Patients with Pancreatic Cancer

  Schultz, N. A., Christensen, I. J., Werner, J., Giese, N., Jensen, B. V., Larsen, O., Bjerregaard, J. K., Pfeiffer, P., Calatayud, D., Nielsen, S. E., Yilmaz, M. K., Holländer, N. H., Wøjdemann, M., Bojesen, S. E., Nielsen, K. R. & Johansen, J. S., 26 jun. 2013, I: P L o S One. 8, 6, s. 1-9 9 s., e67059.

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  • pancreatic neoplasms 100%
  • Biomarkers 79%
  • Odds Ratio 73%
  • interleukin-6 68%
  • Cancer 63%
  24 Citationer (Scopus)
• 2010

  Effect of hyperbaric oxygen therapy on whole blood cyanide concentrations in carbon monoxide intoxicated patients from fire accidents

  Lawson-Smith, P., Jansen, E. C., Hilsted, L. & Larsen, O. H., 15 jun. 2010, I: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 18, s. 32

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  • Cyanides 100%
  • Hyperbaric Oxygenation 98%
  • Carbon Monoxide 78%
  • Accidents 70%
  • Hydrogen Cyanide 23%
  19 Citationer (Scopus)
• 2009

  Effect of oxygen breathing and perfluorocarbon emulsion treatment on air bubbles in adipose tissue during decompression sickness

  Randsoe, T. & Hyldegaard, O., 2009, I: Journal of Applied Physiology. 107, 6, s. 1857-63 6 s.

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  • Decompression Sickness 100%
  • Fluorocarbons 93%
  • Emulsions 72%
  • Adipose Tissue 56%
  • Respiration 55%
  18 Citationer (Scopus)
• 2008

  Effect of oxygen and heliox breathing on air bubbles in adipose tissue during 25-kPa altitude exposures

  Randsoe, T., Kvist, T. M. & Hyldegaard, O., 2008, I: Journal of Applied Physiology. 105, 5, s. 1492-1497 5 s.

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  4 Citationer (Scopus)

• Treatment of cyanide poisoning with HBO

  Lawson-Smith, P., Jansen, E. C., Hilsted, L., Johnsen, A. H. & Hyldegaard, O., 2008, I: Undersea & Hyperbaric Medicine. 35, s. 303-

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