Abstract
This review argues that cholecystokinin (CCK) and gastrin are incretins. The insulin cells are equipped with CCK 2 /gastrin receptors. CCK/gastrin peptides stimulate insulin secretion and potentiate the incretin effect of glucagon-like peptide-1. CCK/gastrin and insulin are released in significant amounts during normal mixed meals even at modest changes in blood glucose concentrations.
Original language | English |
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Journal | Cardiovascular Endocrinology (Online) |
Volume | 5 |
Issue number | 3 |
Pages (from-to) | 99-101 |
ISSN | 2162-688X |
DOIs | |
Publication status | Published - Sept 2016 |