Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin

D Rasmussen; A Bremmelgaard; F Rasmussen; Jørgen Mogens Thorup

Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin

D Rasmussen, A Bremmelgaard, F Rasmussen, Jørgen Mogens Thorup

5 Citations (Scopus)

Abstract

Fifty-nine patients with severe urinary tract infections were treated with either cefotaxime or ampicillin plus netilmicin in a controlled, open randomised study of the clinical and bacteriological effects. The patients responded favourably in both groups. The minimum inhibitory concentrations of cefotaxime against the isolates from blood were low for all bacterial strains except one (Streptococcus faecalis). Time to normalisation of temperature was significantly shorter in the cefotaxime group. The results suggest that cefotaxime is an effective and well-tolerated agent in the treatment of serious infections. However, the difference between the two groups was too small to allow preference of one procedure over the other.

Original language	English
Journal	Danish Medical Bulletin
Volume	33
Issue number	1
Pages (from-to)	49-51
Number of pages	3
ISSN	0907-8916
Publication status	Published - Feb 1986

Keywords

Ampicillin
Cefotaxime
Drug Therapy, Combination
Female
Humans
Male
Middle Aged
Netilmicin
Sepsis
Surgical Wound Infection
Urinary Tract Infections

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title = "Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin",

abstract = "Fifty-nine patients with severe urinary tract infections were treated with either cefotaxime or ampicillin plus netilmicin in a controlled, open randomised study of the clinical and bacteriological effects. The patients responded favourably in both groups. The minimum inhibitory concentrations of cefotaxime against the isolates from blood were low for all bacterial strains except one (Streptococcus faecalis). Time to normalisation of temperature was significantly shorter in the cefotaxime group. The results suggest that cefotaxime is an effective and well-tolerated agent in the treatment of serious infections. However, the difference between the two groups was too small to allow preference of one procedure over the other.",

keywords = "Ampicillin, Cefotaxime, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Netilmicin, Sepsis, Surgical Wound Infection, Urinary Tract Infections",

author = "D Rasmussen and A Bremmelgaard and F Rasmussen and Thorup, {J{\o}rgen Mogens}",

year = "1986",

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T1 - Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin

AU - Rasmussen, D

AU - Bremmelgaard, A

AU - Rasmussen, F

AU - Thorup, Jørgen Mogens

PY - 1986/2

Y1 - 1986/2

N2 - Fifty-nine patients with severe urinary tract infections were treated with either cefotaxime or ampicillin plus netilmicin in a controlled, open randomised study of the clinical and bacteriological effects. The patients responded favourably in both groups. The minimum inhibitory concentrations of cefotaxime against the isolates from blood were low for all bacterial strains except one (Streptococcus faecalis). Time to normalisation of temperature was significantly shorter in the cefotaxime group. The results suggest that cefotaxime is an effective and well-tolerated agent in the treatment of serious infections. However, the difference between the two groups was too small to allow preference of one procedure over the other.

AB - Fifty-nine patients with severe urinary tract infections were treated with either cefotaxime or ampicillin plus netilmicin in a controlled, open randomised study of the clinical and bacteriological effects. The patients responded favourably in both groups. The minimum inhibitory concentrations of cefotaxime against the isolates from blood were low for all bacterial strains except one (Streptococcus faecalis). Time to normalisation of temperature was significantly shorter in the cefotaxime group. The results suggest that cefotaxime is an effective and well-tolerated agent in the treatment of serious infections. However, the difference between the two groups was too small to allow preference of one procedure over the other.

KW - Ampicillin

KW - Cefotaxime

KW - Drug Therapy, Combination

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Netilmicin

KW - Sepsis

KW - Surgical Wound Infection

KW - Urinary Tract Infections

M3 - Journal article

C2 - 3948539

SN - 2245-1919

VL - 33

SP - 49

EP - 51

JO - Danish Medical Journal

JF - Danish Medical Journal

IS - 1

ER -

Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin

Abstract

Keywords

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