Abstract
Severe sepsis is a leading cause of death characterised by infection-induced endothelial and cardiac dysfunction leading to hypovolaemia, maldistribution of flow, tissue ischaemia and organ failure. A clinical approach with focus on cardiovascular diagnostics and rational goal-directed therapy is likely to reduce the high mortality. The treatment involves focus control, broad-spectrum antibiotics, target-oriented fluid therapy and vasopressor and inotropic agents guided by frequent reassessments of the patient's response to treatment.
| Translated title of the contribution | [Early identification and treatment of cardiovascular failure in severe sepsis] |
|---|---|
| Original language | Danish |
| Journal | Ugeskrift for Laeger |
| Volume | 172 |
| Issue number | 3 |
| Pages (from-to) | 210-4 |
| Number of pages | 5 |
| ISSN | 0041-5782 |
| Publication status | Published - 18 Jan 2010 |