TY - BOOK
T1 - The Genomic History of Trondheim
AU - Lundstrøm, Inge Kristine Conrad
PY - 2018
Y1 - 2018
N2 - In recent years there has been a revolutionary expansion of molecular biologytechniques that has enabled achievement of multiple unbelievable milestones when applied toancient remains. This has helped lead to the new discipline, Palaeogenomics. Though it isstill challenging and costly to work with ancient samples, the technological advances haveenabled researchers to no longer being limited to single marker and single sample studies.Now it is possible to study ancient full genomes of multiple individuals, and even severalhundred individuals. The increasing output of sequence data has called for another newdiscipline, Bioinformatics.The work presented in this PhD thesis has been performed using state of the artsequencing techniques and population genomic analysis on data produced from humanskeletal material from the last millennium from Trondheim, Norway. During the MiddleAges the population of Europe suffered from a series of epidemics, worst of all was theplague pandemic known as the Black Death that started around 1350 AD, and caused amassive population reduction by as much as ~50% all over Europe and Western Asia. Theinvestigation of the possible genomic consequences of the medieval plague pandemic is themain aim of this thesis.
AB - In recent years there has been a revolutionary expansion of molecular biologytechniques that has enabled achievement of multiple unbelievable milestones when applied toancient remains. This has helped lead to the new discipline, Palaeogenomics. Though it isstill challenging and costly to work with ancient samples, the technological advances haveenabled researchers to no longer being limited to single marker and single sample studies.Now it is possible to study ancient full genomes of multiple individuals, and even severalhundred individuals. The increasing output of sequence data has called for another newdiscipline, Bioinformatics.The work presented in this PhD thesis has been performed using state of the artsequencing techniques and population genomic analysis on data produced from humanskeletal material from the last millennium from Trondheim, Norway. During the MiddleAges the population of Europe suffered from a series of epidemics, worst of all was theplague pandemic known as the Black Death that started around 1350 AD, and caused amassive population reduction by as much as ~50% all over Europe and Western Asia. Theinvestigation of the possible genomic consequences of the medieval plague pandemic is themain aim of this thesis.
UR - https://rex.kb.dk/primo-explore/fulldisplay?docid=KGL01011006901&context=L&vid=NUI&search_scope=KGL&tab=default_tab&lang=da_DK
M3 - Ph.D. thesis
BT - The Genomic History of Trondheim
PB - Natural History Museum of Denmark, Faculty of Science, University of Copenhagen
ER -