Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

K C Nicolaou; K Namoto; J Li; A Ritzén; T Ulven; M Shoji; D Zaharevitz; R Gussio; D L Sackett; R D Ward; A Hensler; T Fojo; P Giannakakou

Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

K C Nicolaou, K Namoto, J Li, A Ritzén, T Ulven, M Shoji, D Zaharevitz, R Gussio, D L Sackett, R D Ward, A Hensler, T Fojo, P Giannakakou

36 Citations (Scopus)

Abstract

Udgivelsesdato: 2001-Jan-8

Original language	English
Journal	ChemBioChem
Volume	2
Issue number	1
Pages (from-to)	69-75
Number of pages	7
ISSN	1439-4227
Publication status	Published - 8 Jan 2001

Keywords

Antineoplastic Agents
Drug Resistance, Neoplasm
Drug Screening Assays, Antitumor
Epothilones
Humans
Indicators and Reagents
Lactones
Microscopy, Electron
Models, Molecular
Stereoisomerism
Thiazoles
Tubulin
Tumor Cells, Cultured

Cite this

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title = "Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones",

abstract = "Udgivelsesdato: 2001-Jan-8",

keywords = "Antineoplastic Agents, Drug Resistance, Neoplasm, Drug Screening Assays, Antitumor, Epothilones, Humans, Indicators and Reagents, Lactones, Microscopy, Electron, Models, Molecular, Stereoisomerism, Thiazoles, Tubulin, Tumor Cells, Cultured",

author = "Nicolaou, {K C} and K Namoto and J Li and A Ritz{\'e}n and T Ulven and M Shoji and D Zaharevitz and R Gussio and Sackett, {D L} and Ward, {R D} and A Hensler and T Fojo and P Giannakakou",

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day = "8",

language = "English",

volume = "2",

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TY - JOUR

T1 - Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

AU - Nicolaou, K C

AU - Namoto, K

AU - Li, J

AU - Ritzén, A

AU - Ulven, T

AU - Shoji, M

AU - Zaharevitz, D

AU - Gussio, R

AU - Sackett, D L

AU - Ward, R D

AU - Hensler, A

AU - Fojo, T

AU - Giannakakou, P

PY - 2001/1/8

Y1 - 2001/1/8

N2 - Udgivelsesdato: 2001-Jan-8

AB - Udgivelsesdato: 2001-Jan-8

KW - Antineoplastic Agents

KW - Drug Resistance, Neoplasm

KW - Drug Screening Assays, Antitumor

KW - Epothilones

KW - Humans

KW - Indicators and Reagents

KW - Lactones

KW - Microscopy, Electron

KW - Models, Molecular

KW - Stereoisomerism

KW - Thiazoles

KW - Tubulin

KW - Tumor Cells, Cultured

M3 - Journal article

SN - 1439-4227

VL - 2

SP - 69

EP - 75

JO - ChemBioChem

JF - ChemBioChem

IS - 1

ER -

Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

Abstract

Keywords

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