Probabilistic shortest path tractography in DTI using gaussian process ODE solvers

Michael Schober; Niklas Kasenburg; Aasa Feragen; Philipp Hennig; Søren Hauberg

doi:10.1007/978-3-319-10443-0_34

Probabilistic shortest path tractography in DTI using gaussian process ODE solvers

Michael Schober, Niklas Kasenburg, Aasa Feragen, Philipp Hennig, Søren Hauberg

Department of Computer Science

20 Citations (Scopus)

Abstract

Tractography in diffusion tensor imaging estimates connectivity in the brain through observations of local diffusivity. These observations are noisy and of low resolution and, as a consequence, connections cannot be found with high precision. We use probabilistic numerics to estimate connectivity between regions of interest and contribute a Gaussian Process tractography algorithm which allows for both quantification and visualization of its posterior uncertainty. We use the uncertainty both in visualization of individual tracts as well as in heat maps of tract locations. Finally, we provide a quantitative evaluation of different metrics and algorithms showing that the adjoint metric [8] combined with our algorithm produces paths which agree most often with experts.

Original language	English
Title of host publication	Medical image computing and computer-assisted intervention – MICCAI 2014 : 17th International Conference, Boston, MA, USA, September 14-18, 2014, Proceedings, Part III
Editors	Polina Golland, Nobuhiko Hata, Christian Barillot, Joachim Hornegger, Robert Howe
Number of pages	8
Publisher	Springer
Publication date	2014
Pages	265-272
Chapter	34
ISBN (Print)	978-3-319-10442-3
DOIs	https://doi.org/10.1007/978-3-319-10443-0_34
Publication status	Published - 2014
Event	International Conference, MICCAI 2014 - Boston, United States Duration: 14 Sept 2014 → 18 Sept 2014 Conference number: 17

Conference

Conference	International Conference, MICCAI 2014
Number	17
Country/Territory	United States
City	Boston
Period	14/09/2014 → 18/09/2014

Series	Lecture notes in computer science
Volume	8675
ISSN	0302-9743

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Schober, M., Kasenburg, N., Feragen, A., Hennig, P., & Hauberg, S. (2014). Probabilistic shortest path tractography in DTI using gaussian process ODE solvers. In P. Golland, N. Hata, C. Barillot, J. Hornegger, & R. Howe (Eds.), Medical image computing and computer-assisted intervention – MICCAI 2014: 17th International Conference, Boston, MA, USA, September 14-18, 2014, Proceedings, Part III (pp. 265-272). Springer. Lecture notes in computer science Vol. 8675 https://doi.org/10.1007/978-3-319-10443-0_34

Probabilistic shortest path tractography in DTI using gaussian process ODE solvers. / Schober, Michael; Kasenburg, Niklas; Feragen, Aasa et al.

Medical image computing and computer-assisted intervention – MICCAI 2014: 17th International Conference, Boston, MA, USA, September 14-18, 2014, Proceedings, Part III. ed. / Polina Golland; Nobuhiko Hata; Christian Barillot; Joachim Hornegger; Robert Howe. Springer, 2014. p. 265-272 (Lecture notes in computer science, Vol. 8675).

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Schober, M, Kasenburg, N, Feragen, A, Hennig, P & Hauberg, S 2014, Probabilistic shortest path tractography in DTI using gaussian process ODE solvers. in P Golland, N Hata, C Barillot, J Hornegger & R Howe (eds), Medical image computing and computer-assisted intervention – MICCAI 2014: 17th International Conference, Boston, MA, USA, September 14-18, 2014, Proceedings, Part III. Springer, Lecture notes in computer science, vol. 8675, pp. 265-272, International Conference, MICCAI 2014, Boston, United States, 14/09/2014. https://doi.org/10.1007/978-3-319-10443-0_34

Schober M, Kasenburg N, Feragen A, Hennig P, Hauberg S. Probabilistic shortest path tractography in DTI using gaussian process ODE solvers. In Golland P, Hata N, Barillot C, Hornegger J, Howe R, editors, Medical image computing and computer-assisted intervention – MICCAI 2014: 17th International Conference, Boston, MA, USA, September 14-18, 2014, Proceedings, Part III. Springer. 2014. p. 265-272. (Lecture notes in computer science, Vol. 8675). doi: 10.1007/978-3-319-10443-0_34

Schober, Michael ; Kasenburg, Niklas ; Feragen, Aasa et al. / Probabilistic shortest path tractography in DTI using gaussian process ODE solvers. Medical image computing and computer-assisted intervention – MICCAI 2014: 17th International Conference, Boston, MA, USA, September 14-18, 2014, Proceedings, Part III. editor / Polina Golland ; Nobuhiko Hata ; Christian Barillot ; Joachim Hornegger ; Robert Howe. Springer, 2014. pp. 265-272 (Lecture notes in computer science, Vol. 8675).

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Probabilistic shortest path tractography in DTI using gaussian process ODE solvers

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