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Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension
Nina Mertz
,
Susan Weng Larsen
,
Jesper Kristensen
,
Jesper Østergaard
,
Claus Larsen
8
Citations (Scopus)
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Dive into the research topics of 'Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension'. Together they form a unique fingerprint.
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Medicine & Life Sciences
Carbon
8%
Dialysis
6%
Diclofenac
95%
Esterases
9%
Esters
82%
Hydrolysis
7%
imidazole
10%
In Vitro Techniques
3%
Injections
46%
Joints
57%
Kinetics
58%
Oxindoles
14%
Pharmaceutical Preparations
3%
phenylacetic acid
12%
Prodrugs
90%
Solubility
16%
Suspensions
71%
Synovial Fluid
9%
Chemical Compounds
Aqueous Solution
4%
Carbon Atom
3%
Cleavage
5%
Dialysis
7%
Diclofenac
100%
Dissolution
6%
Drug
4%
Ester
49%
Ethyl
5%
Hydrolysis
5%
Indolinone
13%
Length
4%
pH Value
10%
Phenylacetate
10%
Plasma
5%
Prodrug
86%
Reaction Yield
3%
Solubility
10%
Suspension
62%