Abstract
Long-acting bronchodilators are the mainstay of pharmacological therapy for chronic obstructive pulmonary disease (COPD). This paper reviews the efficacy of the once-daily fixed-dose dual bronchodilator combination of indacaterol and glycopyrronium in COPD patients. Compared with single therapy with indacaterol, glycopyrronium and tiotropium and fixed combination salmeterol/fluticasone, fixed-dose indacaterol/glycopyrronium has clinically relevant effects on symptoms, health status, lung function, and rate of exacerbations and by that suggests a potential for dual bronchodilation as an important maintenance therapeutic option for some patients with COPD.
| Translated title of the contribution | The combination of indacaterol and glycopyrronium has effects on symptoms, lung function, and rate of exacerbations in COPD patients. |
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| Original language | Danish |
| Journal | Ugeskrift for Laeger |
| Volume | 176 |
| Issue number | 38 |
| Pages (from-to) | 2-6 |
| Number of pages | 5 |
| ISSN | 0041-5782 |
| Publication status | Published - 15 Sept 2014 |