Irritable bowel syndrome, the microbiota and the gut-brain axis

Hans Raskov; Jakob Burcharth; Hans-Christian Pommergaard; Jacob Rosenberg

doi:10.1080/19490976.2016.1218585

Irritable bowel syndrome, the microbiota and the gut-brain axis

Hans Raskov, Jakob Burcharth, Hans-Christian Pommergaard, Jacob Rosenberg

Department of Clinical Medicine

37 Citations (Scopus)

Abstract

Irritable bowel syndrome is a common functional gastrointestinal disorder and it is now evident that irritable bowel syndrome is a multi-factorial complex of changes in microbiota and immunology. The bidirectional neurohumoral integrated communication between the microbiota and the autonomous nervous system is called the gut-brain-axis, which integrates brain and GI functions, such as gut motility, appetite and weight. The gut-brain-axis has a central function in the perpetuation of irritable bowel syndrome and the microbiota plays a critical role. The purpose of this article is to review recent research concerning the epidemiology of irritable bowel syndrome, influence of microbiota, probiota, gut-brain-axis, and possible treatment modalities on irritable bowel syndrome.

Original language	English
Journal	Gut Microbes
Volume	7
Issue number	5
Pages (from-to)	365-383
Number of pages	19
ISSN	1949-0976
DOIs	https://doi.org/10.1080/19490976.2016.1218585
Publication status	Published - 2 Sept 2016

Access to Document

10.1080/19490976.2016.1218585

19490976.2016.1218585?needAccess=trueFinal published version, 1.05 MB

Cite this

@article{f9a93da9273544fa933541b315105101,

title = "Irritable bowel syndrome, the microbiota and the gut-brain axis",

abstract = "Irritable bowel syndrome is a common functional gastrointestinal disorder and it is now evident that irritable bowel syndrome is a multi-factorial complex of changes in microbiota and immunology. The bidirectional neurohumoral integrated communication between the microbiota and the autonomous nervous system is called the gut-brain-axis, which integrates brain and GI functions, such as gut motility, appetite and weight. The gut-brain-axis has a central function in the perpetuation of irritable bowel syndrome and the microbiota plays a critical role. The purpose of this article is to review recent research concerning the epidemiology of irritable bowel syndrome, influence of microbiota, probiota, gut-brain-axis, and possible treatment modalities on irritable bowel syndrome.",

author = "Hans Raskov and Jakob Burcharth and Hans-Christian Pommergaard and Jacob Rosenberg",

year = "2016",

month = sep,

day = "2",

doi = "10.1080/19490976.2016.1218585",

language = "English",

volume = "7",

pages = "365--383",

journal = "Gut Microbes",

issn = "1949-0976",

publisher = "Taylor & Francis",

number = "5",

}

TY - JOUR

T1 - Irritable bowel syndrome, the microbiota and the gut-brain axis

AU - Raskov, Hans

AU - Burcharth, Jakob

AU - Pommergaard, Hans-Christian

AU - Rosenberg, Jacob

PY - 2016/9/2

Y1 - 2016/9/2

N2 - Irritable bowel syndrome is a common functional gastrointestinal disorder and it is now evident that irritable bowel syndrome is a multi-factorial complex of changes in microbiota and immunology. The bidirectional neurohumoral integrated communication between the microbiota and the autonomous nervous system is called the gut-brain-axis, which integrates brain and GI functions, such as gut motility, appetite and weight. The gut-brain-axis has a central function in the perpetuation of irritable bowel syndrome and the microbiota plays a critical role. The purpose of this article is to review recent research concerning the epidemiology of irritable bowel syndrome, influence of microbiota, probiota, gut-brain-axis, and possible treatment modalities on irritable bowel syndrome.

AB - Irritable bowel syndrome is a common functional gastrointestinal disorder and it is now evident that irritable bowel syndrome is a multi-factorial complex of changes in microbiota and immunology. The bidirectional neurohumoral integrated communication between the microbiota and the autonomous nervous system is called the gut-brain-axis, which integrates brain and GI functions, such as gut motility, appetite and weight. The gut-brain-axis has a central function in the perpetuation of irritable bowel syndrome and the microbiota plays a critical role. The purpose of this article is to review recent research concerning the epidemiology of irritable bowel syndrome, influence of microbiota, probiota, gut-brain-axis, and possible treatment modalities on irritable bowel syndrome.

U2 - 10.1080/19490976.2016.1218585

DO - 10.1080/19490976.2016.1218585

M3 - Review

C2 - 27472486

SN - 1949-0976

VL - 7

SP - 365

EP - 383

JO - Gut Microbes

JF - Gut Microbes

IS - 5

ER -

Irritable bowel syndrome, the microbiota and the gut-brain axis

Abstract

Access to Document

Fingerprint

Cite this