Insulin rescues the unicellular eukaryote Tetrahymena from dying in a complete, synthetic nutrient medium

Søren Tvorup Christensen

doi:10.1006/cbir.1993.1145

Insulin rescues the unicellular eukaryote Tetrahymena from dying in a complete, synthetic nutrient medium

42 Citations (Scopus)

Abstract

The presence of 10(-6) M bovine insulin in chemically defined nutrient medium prevented cell death and improved cell proliferation of the ciliate Tetrahymena pyriformis when inoculated at low initial cell density. The action of insulin was found to be restricted to the 22-30 fragment of the B-chain. These results suggest that small peptides are involved in regulation of cell survival and cell proliferation in Tetrahymena pyriformis.

Original language	English
Journal	Cell Biology International
Volume	17
Issue number	9
Pages (from-to)	833-7
Number of pages	4
ISSN	1065-6995
DOIs	https://doi.org/10.1006/cbir.1993.1145
Publication status	Published - 1993
Externally published	Yes

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10.1006/cbir.1993.1145

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title = "Insulin rescues the unicellular eukaryote Tetrahymena from dying in a complete, synthetic nutrient medium",

abstract = "The presence of 10(-6) M bovine insulin in chemically defined nutrient medium prevented cell death and improved cell proliferation of the ciliate Tetrahymena pyriformis when inoculated at low initial cell density. The action of insulin was found to be restricted to the 22-30 fragment of the B-chain. These results suggest that small peptides are involved in regulation of cell survival and cell proliferation in Tetrahymena pyriformis.",

author = "Christensen, {S{\o}ren Tvorup}",

note = "Keywords: Amino Acid Sequence; Animals; Cattle; Cell Division; Culture Media, Serum-Free; Insulin; Molecular Sequence Data; Tetrahymena pyriformis",

year = "1993",

doi = "10.1006/cbir.1993.1145",

language = "English",

volume = "17",

pages = "833--7",

journal = "Cell Biology International",

issn = "1065-6995",

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T1 - Insulin rescues the unicellular eukaryote Tetrahymena from dying in a complete, synthetic nutrient medium

AU - Christensen, Søren Tvorup

N1 - Keywords: Amino Acid Sequence; Animals; Cattle; Cell Division; Culture Media, Serum-Free; Insulin; Molecular Sequence Data; Tetrahymena pyriformis

PY - 1993

Y1 - 1993

N2 - The presence of 10(-6) M bovine insulin in chemically defined nutrient medium prevented cell death and improved cell proliferation of the ciliate Tetrahymena pyriformis when inoculated at low initial cell density. The action of insulin was found to be restricted to the 22-30 fragment of the B-chain. These results suggest that small peptides are involved in regulation of cell survival and cell proliferation in Tetrahymena pyriformis.

AB - The presence of 10(-6) M bovine insulin in chemically defined nutrient medium prevented cell death and improved cell proliferation of the ciliate Tetrahymena pyriformis when inoculated at low initial cell density. The action of insulin was found to be restricted to the 22-30 fragment of the B-chain. These results suggest that small peptides are involved in regulation of cell survival and cell proliferation in Tetrahymena pyriformis.

U2 - 10.1006/cbir.1993.1145

DO - 10.1006/cbir.1993.1145

M3 - Journal article

C2 - 8220309

SN - 1065-6995

VL - 17

SP - 833

EP - 837

JO - Cell Biology International

JF - Cell Biology International

IS - 9

ER -

Insulin rescues the unicellular eukaryote Tetrahymena from dying in a complete, synthetic nutrient medium

Abstract

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