Homochiral growth through enantiomeric cross-inhibition

TY - JOUR

T1 - Homochiral growth through enantiomeric cross-inhibition

AU - Brandenburg, A.

AU - Andersen, A. C.

AU - Höfner, S.

AU - Nilsson, M.

PY - 2005/6/1

Y1 - 2005/6/1

N2 - The stability and conservation properties of a recently proposed polymerization model are studied. The achiral (racemic) solution is linearly unstable once the relevant control parameter (here the fidelity of the catalyst) exceeds a critical value. The growth rate is calculated for different fidelity parameters and cross-inhibition rates. A chirality parameter is defined and shown to be conserved by the nonlinear terms of the model. Finally, a truncated version of the model is used to derive a set of two ordinary differential equations and it is argued that these equations are more realistic than those used in earlier models of that form.

AB - The stability and conservation properties of a recently proposed polymerization model are studied. The achiral (racemic) solution is linearly unstable once the relevant control parameter (here the fidelity of the catalyst) exceeds a critical value. The growth rate is calculated for different fidelity parameters and cross-inhibition rates. A chirality parameter is defined and shown to be conserved by the nonlinear terms of the model. Finally, a truncated version of the model is used to derive a set of two ordinary differential equations and it is argued that these equations are more realistic than those used in earlier models of that form.

KW - DNA polymerization

KW - Enantiomeric cross-inhibition

KW - Origin of homochirality

UR - http://www.scopus.com/inward/record.url?scp=26844431512&partnerID=8YFLogxK

U2 - 10.1007/s11084-005-0656-9

DO - 10.1007/s11084-005-0656-9

M3 - Journal article

C2 - 16228640

AN - SCOPUS:26844431512

SN - 0169-6149

VL - 35

SP - 225

EP - 241

JO - Origins of Life and Evolution of Biospheres

JF - Origins of Life and Evolution of Biospheres

IS - 3

ER -