Future risk of diabetes in mother and child after gestational diabetes mellitus

TY - JOUR

T1 - Future risk of diabetes in mother and child after gestational diabetes mellitus

AU - Damm, Peter

AU - Damm, Peter

N1 - Keywords: Adult; Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Hyperglycemia; Metabolic Syndrome X; Prediabetic State; Pregnancy; Pregnancy Complications; Risk Factors; Young Adult

PY - 2009/3/1

Y1 - 2009/3/1

N2 - Gestational diabetes mellitus (GDM) is a common pregnancy complication with increased maternal and perinatal morbidity. However, significant long-term morbidity also exists for the mother and offspring. Women with previous GDM have a very high risk of developing overt diabetes, primarily type 2 diabetes, later in life. Moreover, the risk of the metabolic syndrome is increased 3-fold in these women. Their offspring have an 8-fold risk of diabetes/prediabetes at 19-27 years of age. Thus, GDM is part of a vicious circle which increases the development of diabetes in the coming generations.

AB - Gestational diabetes mellitus (GDM) is a common pregnancy complication with increased maternal and perinatal morbidity. However, significant long-term morbidity also exists for the mother and offspring. Women with previous GDM have a very high risk of developing overt diabetes, primarily type 2 diabetes, later in life. Moreover, the risk of the metabolic syndrome is increased 3-fold in these women. Their offspring have an 8-fold risk of diabetes/prediabetes at 19-27 years of age. Thus, GDM is part of a vicious circle which increases the development of diabetes in the coming generations.

U2 - 10.1016/j.ijgo.2008.11.025

DO - 10.1016/j.ijgo.2008.11.025

M3 - Journal article

SN - 0020-7292

VL - 104 Suppl 1

SP - S25-6

JO - International Journal of Gynecology & Obstetrics

JF - International Journal of Gynecology & Obstetrics

ER -