Feature-space transformation improves supervised segmentation across scanners

Annegreet van Opbroek*, Hakim C. Achterberg, Marleen de Bruijne

*Corresponding author for this work
3 Citations (Scopus)

Abstract

Image-segmentation techniques based on supervised classification generally perform well on the condition that training and test samples have the same feature distribution. However, if training and test images are acquired with different scanners or scanning parameters, their feature distributions can be very different, which can hurt the performance of such techniques. We propose a feature-space-transformation method to overcome these differences in feature distributions. Our method learns a mapping of the feature values of training voxels to values observed in images from the test scanner. This transformation is learned from unlabeled images of subjects scanned on both the training scanner and the test scanner. We evaluated our method on hippocampus segmentation on 27 images of the Harmonized Hippocampal Protocol (HarP), a heterogeneous dataset consisting of 1.5T and 3T MR images. The results showed that our feature space transformation improved the Dice overlap of segmentations obtained with an SVM classifier from 0.36 to 0.85 when only 10 atlases were used and from 0.79 to 0.85 when around 100 atlases were used.

Original languageEnglish
Title of host publicationMachine learning meets medical imaging : First International Workshop, MLMMI 2015, Held in Conjunction with ICML 2015, Lille, France, July 11, 2015, Revised Selected Papers
Number of pages9
PublisherSpringer
Publication date2015
Pages85-93
DOIs
Publication statusPublished - 2015
Event1st International Workshop on Machine Learning Meets Medical Imaging, MLMMI 2015 - Lille, France
Duration: 11 Jul 201511 Jul 2015

Conference

Conference1st International Workshop on Machine Learning Meets Medical Imaging, MLMMI 2015
Country/TerritoryFrance
CityLille
Period11/07/201511/07/2015
SeriesLecture notes in computer science
Volume9487
ISSN0302-9743

Keywords

  • Brain
  • Hippocampus
  • Machine learning
  • MRI
  • Transfer learning

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