Abstract
We report on the fabrication of a microfluidic cell completely made of thiol-ene for microarray applications. To overcome the issues related to the hydrophobic nature of the thiol-ene material we have also introduced a new polymeric coating based of N, N-dimethylacrylamide (DMA) which is able to reduce the material hydrophobicity, to avoid aspecific protein binding and, thanks to the functional monomer propinyl mathacrylate, it is able to bind, in an oriented way, azido modified biomolecules.
| Original language | English |
|---|---|
| Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
| Number of pages | 3 |
| Publisher | Chemical and Biological Microsystems Society |
| Publication date | 2014 |
| Pages | 1719-1721 |
| ISBN (Electronic) | 9780979806476 |
| Publication status | Published - 2014 |
| Event | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: 26 Oct 2014 → 30 Oct 2014 |
Conference
| Conference | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
|---|---|
| Country/Territory | United States |
| City | San Antonio |
| Period | 26/10/2014 → 30/10/2014 |
| Sponsor | Analytical Chemistry, CBMS, Indiana University (IU), Institute of Microchemical Technology (IMT), LPKF Laser and Electronics |
Keywords
- Antibody oriented immobilization
- Coatings
- Microarray
- Microfluidics
- Thiol-ene