Diagnostic accuracy of MR colonography with fecal tagging

Michael Patrick Achiam; Vibeke Berg Løgager; Elizaveta Chabanova; Bodil Eegholm; Henrik Segelcke Thomsen; Jacob Rosenberg

doi:10.1007/s00261-008-9402-x

Diagnostic accuracy of MR colonography with fecal tagging

Michael Patrick Achiam, Vibeke Berg Løgager, Elizaveta Chabanova, Bodil Eegholm, Henrik Segelcke Thomsen, Jacob Rosenberg

23 Citations (Scopus)

Abstract

BACKGROUND: MR colonography (MRC) is a non-invasive method of examining the colon, but it is still only used in a few specialized centers on a daily basis. The purpose of this study was to evaluate the performance of MRC with improved fecal tagging vs. conventional colonoscopy (CC). METHODS: Between March 2006 and February 2007, consecutive patients who received first-time referrals to CC were asked to participate in the study. Two days prior to MRC, a new contrast mixture (barium/ferumoxsil) was ingested together with four meals each day. Standard bowel cleansing was performed before CC. MRC was evaluated by two blinded observers. MRC results were compared with CC. RESULTS: A total of 56 patients were included. The per-polyp sensitivity was 85.7% for polyps 6-10 mm and 81.3% for polyps >10 mm. The per-patient sensitivity/specificity was 100%/80% for polyps >6 mm and 100%/91.4% for polyps >10 mm. CONCLUSION: MRC showed acceptable per-patient sensitivities, but the per-polyp sensitivities are still compromised by the fecal tagging. MRC may be implemented, but at the present time MRC with fecal tagging is not ready for widespread use, although it remains a very promising diagnostic tool.

Original language	English
Journal	Abdominal Imaging
Volume	34
Issue number	4
Pages (from-to)	483-90
Number of pages	8
ISSN	0942-8925
DOIs	https://doi.org/10.1007/s00261-008-9402-x
Publication status	Published - 2009

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title = "Diagnostic accuracy of MR colonography with fecal tagging",

abstract = "BACKGROUND: MR colonography (MRC) is a non-invasive method of examining the colon, but it is still only used in a few specialized centers on a daily basis. The purpose of this study was to evaluate the performance of MRC with improved fecal tagging vs. conventional colonoscopy (CC). METHODS: Between March 2006 and February 2007, consecutive patients who received first-time referrals to CC were asked to participate in the study. Two days prior to MRC, a new contrast mixture (barium/ferumoxsil) was ingested together with four meals each day. Standard bowel cleansing was performed before CC. MRC was evaluated by two blinded observers. MRC results were compared with CC. RESULTS: A total of 56 patients were included. The per-polyp sensitivity was 85.7% for polyps 6-10 mm and 81.3% for polyps >10 mm. The per-patient sensitivity/specificity was 100%/80% for polyps >6 mm and 100%/91.4% for polyps >10 mm. CONCLUSION: MRC showed acceptable per-patient sensitivities, but the per-polyp sensitivities are still compromised by the fecal tagging. MRC may be implemented, but at the present time MRC with fecal tagging is not ready for widespread use, although it remains a very promising diagnostic tool.",

author = "Achiam, {Michael Patrick} and L{\o}gager, {Vibeke Berg} and Elizaveta Chabanova and Bodil Eegholm and Thomsen, {Henrik Segelcke} and Jacob Rosenberg",

note = "Keywords: Adult; Barium Sulfate; Colonic Diseases; Colonoscopy; Contrast Media; Female; Ferrosoferric Oxide; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Meglumine; Organometallic Compounds; Sensitivity and Specificity; Siloxanes",

year = "2009",

doi = "10.1007/s00261-008-9402-x",

language = "English",

volume = "34",

pages = "483--90",

journal = "Abdominal Imaging",

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T1 - Diagnostic accuracy of MR colonography with fecal tagging

AU - Achiam, Michael Patrick

AU - Løgager, Vibeke Berg

AU - Chabanova, Elizaveta

AU - Eegholm, Bodil

AU - Thomsen, Henrik Segelcke

AU - Rosenberg, Jacob

N1 - Keywords: Adult; Barium Sulfate; Colonic Diseases; Colonoscopy; Contrast Media; Female; Ferrosoferric Oxide; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Meglumine; Organometallic Compounds; Sensitivity and Specificity; Siloxanes

PY - 2009

Y1 - 2009

N2 - BACKGROUND: MR colonography (MRC) is a non-invasive method of examining the colon, but it is still only used in a few specialized centers on a daily basis. The purpose of this study was to evaluate the performance of MRC with improved fecal tagging vs. conventional colonoscopy (CC). METHODS: Between March 2006 and February 2007, consecutive patients who received first-time referrals to CC were asked to participate in the study. Two days prior to MRC, a new contrast mixture (barium/ferumoxsil) was ingested together with four meals each day. Standard bowel cleansing was performed before CC. MRC was evaluated by two blinded observers. MRC results were compared with CC. RESULTS: A total of 56 patients were included. The per-polyp sensitivity was 85.7% for polyps 6-10 mm and 81.3% for polyps >10 mm. The per-patient sensitivity/specificity was 100%/80% for polyps >6 mm and 100%/91.4% for polyps >10 mm. CONCLUSION: MRC showed acceptable per-patient sensitivities, but the per-polyp sensitivities are still compromised by the fecal tagging. MRC may be implemented, but at the present time MRC with fecal tagging is not ready for widespread use, although it remains a very promising diagnostic tool.

AB - BACKGROUND: MR colonography (MRC) is a non-invasive method of examining the colon, but it is still only used in a few specialized centers on a daily basis. The purpose of this study was to evaluate the performance of MRC with improved fecal tagging vs. conventional colonoscopy (CC). METHODS: Between March 2006 and February 2007, consecutive patients who received first-time referrals to CC were asked to participate in the study. Two days prior to MRC, a new contrast mixture (barium/ferumoxsil) was ingested together with four meals each day. Standard bowel cleansing was performed before CC. MRC was evaluated by two blinded observers. MRC results were compared with CC. RESULTS: A total of 56 patients were included. The per-polyp sensitivity was 85.7% for polyps 6-10 mm and 81.3% for polyps >10 mm. The per-patient sensitivity/specificity was 100%/80% for polyps >6 mm and 100%/91.4% for polyps >10 mm. CONCLUSION: MRC showed acceptable per-patient sensitivities, but the per-polyp sensitivities are still compromised by the fecal tagging. MRC may be implemented, but at the present time MRC with fecal tagging is not ready for widespread use, although it remains a very promising diagnostic tool.

U2 - 10.1007/s00261-008-9402-x

DO - 10.1007/s00261-008-9402-x

M3 - Journal article

C2 - 18452023

SN - 2366-004X

VL - 34

SP - 483

EP - 490

JO - Abdominal Imaging

JF - Abdominal Imaging

IS - 4

ER -

Diagnostic accuracy of MR colonography with fecal tagging

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