Abstract
The work presented in this thesis is the result of research carried out during a three-year PhD at the Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, under supervision of Professor Tom Gilbert. The PhD was funded by the Danish National Research Foundation (Danmarks Grundforskningfond) 'Centre of Excellence in GeoGenetics' grant, with additional funding provided by the Danish Council for Independent Research 'Sapere Aude' programme.
The thesis comprises five chapters, all of which represent different projects that involved the analysis of massive amounts of sequence data, generated using next-generation sequencing (NGS) technologies, from either forensic (Chapter 1) or ancient (Chapters 2-5) materials. These chapters present projects very different in nature, reflecting the diversity of questions that have become possible to address in the ancient DNA field, thanks to the introduction of NGS and the implementation of data analysis methods specific for each project.
Chapters 1 to 3 have been published in peer-reviewed journals and Chapter 4 is currently in review. Chapter 5 consists of a manuscript describing initial results of an ongoing research project, for which more data is currently being generated; therefore it should be interpreted as a preliminary report.
In addition to the five chapters, an introduction and five appendices are included.
Appended articles are included for the reader's interest, these represent the collaborations I have been part of during my PhD on which I am not first author, therefore are not to be considered a core part of my PhD work.
The thesis comprises five chapters, all of which represent different projects that involved the analysis of massive amounts of sequence data, generated using next-generation sequencing (NGS) technologies, from either forensic (Chapter 1) or ancient (Chapters 2-5) materials. These chapters present projects very different in nature, reflecting the diversity of questions that have become possible to address in the ancient DNA field, thanks to the introduction of NGS and the implementation of data analysis methods specific for each project.
Chapters 1 to 3 have been published in peer-reviewed journals and Chapter 4 is currently in review. Chapter 5 consists of a manuscript describing initial results of an ongoing research project, for which more data is currently being generated; therefore it should be interpreted as a preliminary report.
In addition to the five chapters, an introduction and five appendices are included.
Appended articles are included for the reader's interest, these represent the collaborations I have been part of during my PhD on which I am not first author, therefore are not to be considered a core part of my PhD work.
| Original language | English |
|---|
| Publisher | Natural History Museum of Denmark, Faculty of Science, University of Copenhagen |
|---|---|
| Number of pages | 249 |
| Publication status | Published - 2012 |