Combating biofilms

Liang Yang; Yang Liu; Hong Wu; Zhijun Song; Niels Høiby; Søren Molin; Michael Givskov

doi:10.1111/j.1574-695x.2011.00858.x

Combating biofilms

Liang Yang, Yang Liu, Hong Wu, Zhijun Song, Niels Høiby, Søren Molin, Michael Givskov

Department of Immunology and Microbiology

132 Citations (Scopus)

Abstract

Biofilms are complex microbial communities consisting of microcolonies embedded in a matrix of self-produced polymer substances. Biofilm cells show much greater resistance to environmental challenges including antimicrobial agents than their free-living counterparts. The biofilm mode of life is believed to significantly contribute to successful microbial survival in hostile environments. Conventional treatment, disinfection and cleaning strategies do not proficiently deal with biofilm-related problems, such as persistent infections and contamination of food production facilities. In this review, strategies to control biofilms are discussed, including those of inhibition of microbial attachment, interference of biofilm structure development and differentiation, killing of biofilm cells and induction of biofilm dispersion.

Original language	English
Journal	F E M S Immunology and Medical Microbiology
Volume	65
Issue number	2
Pages (from-to)	146–157
ISSN	0928-8244
DOIs	https://doi.org/10.1111/j.1574-695x.2011.00858.x
Publication status	Published - Jul 2012

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1574-695x.2011.00858.x

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AU - Yang, Liang

AU - Liu, Yang

AU - Wu, Hong

AU - Song, Zhijun

AU - Høiby, Niels

AU - Molin, Søren

AU - Givskov, Michael

PY - 2012/7

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Combating biofilms

Abstract

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