Cochraneoversigter sammenlignet med firmastøttede og andre metaanalyser af de samme laegemidler

Anders W Jørgensen; Jørgen Hilden; Peter C Gøtzsche

Cochraneoversigter sammenlignet med firmastøttede og andre metaanalyser af de samme laegemidler

Translated title of the contribution: Cochrane reviews compared with industry-supported and other meta-analyses of the same drugs--secondary publication

Anders W Jørgensen, Jørgen Hilden, Peter C Gøtzsche

Section of Biostatistics

3 Citations (Scopus)

Abstract

24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution.
Udgivelsesdato: 2006-Nov-27

Translated title of the contribution	Cochrane reviews compared with industry-supported and other meta-analyses of the same drugs--secondary publication
Original language	Danish
Journal	Ugeskrift for læger
Volume	168
Issue number	48
Pages (from-to)	4218-20
Number of pages	2
ISSN	0041-5782
Publication status	Published - 2006

Cite this

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title = "Cochraneoversigter sammenlignet med firmast{\o}ttede og andre metaanalyser af de samme laegemidler",

abstract = "24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution. Udgivelsesdato: 2006-Nov-27",

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year = "2006",

language = "Dansk",

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T1 - Cochraneoversigter sammenlignet med firmastøttede og andre metaanalyser af de samme laegemidler

AU - Jørgensen, Anders W

AU - Hilden, Jørgen

AU - Gøtzsche, Peter C

PY - 2006

Y1 - 2006

N2 - 24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution. Udgivelsesdato: 2006-Nov-27

AB - 24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution. Udgivelsesdato: 2006-Nov-27

M3 - Tidsskriftartikel

C2 - 17147949

SN - 0041-5782

VL - 168

SP - 4218

EP - 4220

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 48

ER -