Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels

Daniella Bach Pedersen; Peter Koch Jensen; Morten la Cour; Jens Folke Kiilgaard; Thor Eysteinsson; Kurt Bang; Anne Kathrine Wiencke; Einar Stefánsson

doi:http://dx.doi.org/10.1007/s00417-003-0817-3

Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels

Daniella Bach Pedersen, Peter Koch Jensen, Morten la Cour, Jens Folke Kiilgaard, Thor Eysteinsson, Kurt Bang, Anne Kathrine Wiencke, Einar Stefánsson

53 Citations (Scopus)

Abstract

Carbonic anhydrase inhibitors (CAIs) increase blood flow in the brain and probably also in the optic nerve and retina. Additionally they elevate the oxygen tension in the optic nerve in the pig. We propose that they also raise the oxygen tension in the retina. We studied the oxygen tension in the pig retina and optic nerve before and after dorzolamide injection. Also the retinal vessel diameters during carbonic anhydrase inhibition were studied.

Original language	English
Journal	Graefe's Archive for Clinical and Experimental Ophthalmology
Volume	243
Issue number	2
Pages (from-to)	163-8
Number of pages	6
ISSN	0721-832X
DOIs	https://doi.org/10.1007/s00417-003-0817-3
Publication status	Published - 2005

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title = "Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels",

abstract = "Carbonic anhydrase inhibitors (CAIs) increase blood flow in the brain and probably also in the optic nerve and retina. Additionally they elevate the oxygen tension in the optic nerve in the pig. We propose that they also raise the oxygen tension in the retina. We studied the oxygen tension in the pig retina and optic nerve before and after dorzolamide injection. Also the retinal vessel diameters during carbonic anhydrase inhibition were studied.",

author = "Pedersen, {Daniella Bach} and {Koch Jensen}, Peter and {la Cour}, Morten and Kiilgaard, {Jens Folke} and Thor Eysteinsson and Kurt Bang and Wiencke, {Anne Kathrine} and Einar Stef{\'a}nsson",

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T1 - Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels

AU - Pedersen, Daniella Bach

AU - Koch Jensen, Peter

AU - la Cour, Morten

AU - Kiilgaard, Jens Folke

AU - Eysteinsson, Thor

AU - Bang, Kurt

AU - Wiencke, Anne Kathrine

AU - Stefánsson, Einar

PY - 2005

Y1 - 2005

N2 - Carbonic anhydrase inhibitors (CAIs) increase blood flow in the brain and probably also in the optic nerve and retina. Additionally they elevate the oxygen tension in the optic nerve in the pig. We propose that they also raise the oxygen tension in the retina. We studied the oxygen tension in the pig retina and optic nerve before and after dorzolamide injection. Also the retinal vessel diameters during carbonic anhydrase inhibition were studied.

AB - Carbonic anhydrase inhibitors (CAIs) increase blood flow in the brain and probably also in the optic nerve and retina. Additionally they elevate the oxygen tension in the optic nerve in the pig. We propose that they also raise the oxygen tension in the retina. We studied the oxygen tension in the pig retina and optic nerve before and after dorzolamide injection. Also the retinal vessel diameters during carbonic anhydrase inhibition were studied.

U2 - http://dx.doi.org/10.1007/s00417-003-0817-3

DO - http://dx.doi.org/10.1007/s00417-003-0817-3

M3 - Journal article

SN - 0721-832X

VL - 243

SP - 163

EP - 168

JO - Graefe's Archive for Clinical and Experimental Ophthalmology

JF - Graefe's Archive for Clinical and Experimental Ophthalmology

IS - 2

ER -

Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels

Abstract

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