[C-reactive protein and risk of ischaemic vascular and cerebrovascular disease--secondary publication]

J. Zacho; A. Tybjaerg-Hansen; J.S. Jensen; P. Grande; H. Sillesen; B.G. Nordestgaard

[C-reactive protein and risk of ischaemic vascular and cerebrovascular disease--secondary publication]

J. Zacho, A. Tybjaerg-Hansen, J.S. Jensen, P. Grande, H. Sillesen, B.G. Nordestgaard

Abstract

Elevated levels of C reactive protein (CRP) are associated with increased risk of ischaemic vascular disease. We tested whether this is a causal association. CRP > 3 vs < 1 mg/l were associated with an increased risk of ischaemic heart- and cerebrovascular disease of 1.6 and 1.3, respectively. Four CRP polymorphisms were associated with a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of 32% and 25% for ischemic heart- and ischemic cerebrovascular disease, respectively. However, these genotype combinations were not associated with an increased risk of ischaemic vascular disease
Udgivelsesdato: 2009/5/18

Original language	Danish
Journal	Ugeskrift for læger
Volume	171
Issue number	21
Pages (from-to)	1751-1755
Number of pages	4
ISSN	0041-5782
Publication status	Published - 2009

Cite this

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title = "[C-reactive protein and risk of ischaemic vascular and cerebrovascular disease--secondary publication]",

abstract = "Elevated levels of C reactive protein (CRP) are associated with increased risk of ischaemic vascular disease. We tested whether this is a causal association. CRP > 3 vs < 1 mg/l were associated with an increased risk of ischaemic heart- and cerebrovascular disease of 1.6 and 1.3, respectively. Four CRP polymorphisms were associated with a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of 32% and 25% for ischemic heart- and ischemic cerebrovascular disease, respectively. However, these genotype combinations were not associated with an increased risk of ischaemic vascular disease Udgivelsesdato: 2009/5/18",

author = "J. Zacho and A. Tybjaerg-Hansen and J.S. Jensen and P. Grande and H. Sillesen and B.G. Nordestgaard",

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T1 - [C-reactive protein and risk of ischaemic vascular and cerebrovascular disease--secondary publication]

AU - Zacho, J.

AU - Tybjaerg-Hansen, A.

AU - Jensen, J.S.

AU - Grande, P.

AU - Sillesen, H.

AU - Nordestgaard, B.G.

N1 - SEKUNDÆRPUBLIKATION OK/CTU

PY - 2009

Y1 - 2009

N2 - Elevated levels of C reactive protein (CRP) are associated with increased risk of ischaemic vascular disease. We tested whether this is a causal association. CRP > 3 vs < 1 mg/l were associated with an increased risk of ischaemic heart- and cerebrovascular disease of 1.6 and 1.3, respectively. Four CRP polymorphisms were associated with a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of 32% and 25% for ischemic heart- and ischemic cerebrovascular disease, respectively. However, these genotype combinations were not associated with an increased risk of ischaemic vascular disease Udgivelsesdato: 2009/5/18

AB - Elevated levels of C reactive protein (CRP) are associated with increased risk of ischaemic vascular disease. We tested whether this is a causal association. CRP > 3 vs < 1 mg/l were associated with an increased risk of ischaemic heart- and cerebrovascular disease of 1.6 and 1.3, respectively. Four CRP polymorphisms were associated with a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of 32% and 25% for ischemic heart- and ischemic cerebrovascular disease, respectively. However, these genotype combinations were not associated with an increased risk of ischaemic vascular disease Udgivelsesdato: 2009/5/18

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 171

SP - 1751

EP - 1755

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 21

ER -