Ambient and at-the-ear occupational noise exposure and serum lipid levels

Mai C Arlien-Søborg; Astrid S Schmedes; Z A Stokholm; M B Grynderup; J P Bonde; C S Jensen; Å M Hansen; T W Frederiksen; J Kristiansen; K L Christensen; J M Vestergaard; S P Lund; H A Kolstad

doi:10.1007/s00420-016-1145-3

Ambient and at-the-ear occupational noise exposure and serum lipid levels

Mai C Arlien-Søborg, Astrid S Schmedes, Z A Stokholm, M B Grynderup, J P Bonde, C S Jensen, Å M Hansen, T W Frederiksen, J Kristiansen, K L Christensen, J M Vestergaard, S P Lund, H A Kolstad

8 Citations (Scopus)

Abstract

OBJECTIVES: Occupational and residential noise exposure has been related to increased risk of cardiovascular disease. Alteration of serum lipid levels has been proposed as a possible causal pathway. The objective of this study was to investigate the relation between ambient and at-the-ear occupational noise exposure and serum levels of total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, and triglycerides when accounting for well-established predictors of lipid levels.

METHODS: This cross-sectional study included 424 industrial workers and 84 financial workers to obtain contrast in noise exposure levels. They provided a serum sample and wore portable dosimeters that every 5-s recorded ambient noise exposure levels during a 24-h period. We extracted measurements obtained during work and calculated the full-shift mean ambient noise level. For 331 workers who kept a diary on the use of a hearing protection device (HPD), we subtracted 10 dB from every noise recording obtained during HPD use and estimated the mean full-shift noise exposure level at the ear.

RESULTS: Mean ambient noise level was 79.9 dB (A) [range 55.0-98.9] and the mean estimated level at the ear 77.8 dB (A) [range 55.0-94.2]. Ambient and at-the-ear noise levels were strongly associated with increasing levels of triglycerides, cholesterol-HDL ratio, and decreasing levels of HDL-cholesterol, but only in unadjusted analyses that did not account for HPD use and other risk factors.

CONCLUSION: No associations between ambient or at-the-ear occupational noise exposure and serum lipid levels were observed. This indicates that a causal pathway between occupational and residential noise exposure and cardiovascular disease does not include alteration of lipid levels.

Original language	English
Journal	International Archives of Occupational and Environmental Health
Volume	89
Issue number	7
Pages (from-to)	1087-1093
Number of pages	7
ISSN	0340-0131
DOIs	https://doi.org/10.1007/s00420-016-1145-3
Publication status	Published - 1 Oct 2016

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Arlien-Søborg, M. C., Schmedes, A. S., Stokholm, Z. A., Grynderup, M. B., Bonde, J. P., Jensen, C. S., Hansen, Å. M., Frederiksen, T. W., Kristiansen, J., Christensen, K. L., Vestergaard, J. M., Lund, S. P., & Kolstad, H. A. (2016). Ambient and at-the-ear occupational noise exposure and serum lipid levels. International Archives of Occupational and Environmental Health, 89(7), 1087-1093. https://doi.org/10.1007/s00420-016-1145-3

Arlien-Søborg, MC, Schmedes, AS, Stokholm, ZA, Grynderup, MB, Bonde, JP, Jensen, CS, Hansen, ÅM, Frederiksen, TW, Kristiansen, J, Christensen, KL, Vestergaard, JM, Lund, SP & Kolstad, HA 2016, 'Ambient and at-the-ear occupational noise exposure and serum lipid levels', International Archives of Occupational and Environmental Health, vol. 89, no. 7, pp. 1087-1093. https://doi.org/10.1007/s00420-016-1145-3

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title = "Ambient and at-the-ear occupational noise exposure and serum lipid levels",

abstract = "OBJECTIVES: Occupational and residential noise exposure has been related to increased risk of cardiovascular disease. Alteration of serum lipid levels has been proposed as a possible causal pathway. The objective of this study was to investigate the relation between ambient and at-the-ear occupational noise exposure and serum levels of total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, and triglycerides when accounting for well-established predictors of lipid levels.METHODS: This cross-sectional study included 424 industrial workers and 84 financial workers to obtain contrast in noise exposure levels. They provided a serum sample and wore portable dosimeters that every 5-s recorded ambient noise exposure levels during a 24-h period. We extracted measurements obtained during work and calculated the full-shift mean ambient noise level. For 331 workers who kept a diary on the use of a hearing protection device (HPD), we subtracted 10 dB from every noise recording obtained during HPD use and estimated the mean full-shift noise exposure level at the ear.RESULTS: Mean ambient noise level was 79.9 dB (A) [range 55.0-98.9] and the mean estimated level at the ear 77.8 dB (A) [range 55.0-94.2]. Ambient and at-the-ear noise levels were strongly associated with increasing levels of triglycerides, cholesterol-HDL ratio, and decreasing levels of HDL-cholesterol, but only in unadjusted analyses that did not account for HPD use and other risk factors.CONCLUSION: No associations between ambient or at-the-ear occupational noise exposure and serum lipid levels were observed. This indicates that a causal pathway between occupational and residential noise exposure and cardiovascular disease does not include alteration of lipid levels.",

author = "Arlien-S{\o}borg, {Mai C} and Schmedes, {Astrid S} and Stokholm, {Z A} and Grynderup, {M B} and Bonde, {J P} and Jensen, {C S} and Hansen, {{\AA} M} and Frederiksen, {T W} and J Kristiansen and Christensen, {K L} and Vestergaard, {J M} and Lund, {S P} and Kolstad, {H A}",

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doi = "10.1007/s00420-016-1145-3",

language = "English",

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TY - JOUR

T1 - Ambient and at-the-ear occupational noise exposure and serum lipid levels

AU - Arlien-Søborg, Mai C

AU - Schmedes, Astrid S

AU - Stokholm, Z A

AU - Grynderup, M B

AU - Bonde, J P

AU - Jensen, C S

AU - Hansen, Å M

AU - Frederiksen, T W

AU - Kristiansen, J

AU - Christensen, K L

AU - Vestergaard, J M

AU - Lund, S P

AU - Kolstad, H A

PY - 2016/10/1

Y1 - 2016/10/1

N2 - OBJECTIVES: Occupational and residential noise exposure has been related to increased risk of cardiovascular disease. Alteration of serum lipid levels has been proposed as a possible causal pathway. The objective of this study was to investigate the relation between ambient and at-the-ear occupational noise exposure and serum levels of total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, and triglycerides when accounting for well-established predictors of lipid levels.METHODS: This cross-sectional study included 424 industrial workers and 84 financial workers to obtain contrast in noise exposure levels. They provided a serum sample and wore portable dosimeters that every 5-s recorded ambient noise exposure levels during a 24-h period. We extracted measurements obtained during work and calculated the full-shift mean ambient noise level. For 331 workers who kept a diary on the use of a hearing protection device (HPD), we subtracted 10 dB from every noise recording obtained during HPD use and estimated the mean full-shift noise exposure level at the ear.RESULTS: Mean ambient noise level was 79.9 dB (A) [range 55.0-98.9] and the mean estimated level at the ear 77.8 dB (A) [range 55.0-94.2]. Ambient and at-the-ear noise levels were strongly associated with increasing levels of triglycerides, cholesterol-HDL ratio, and decreasing levels of HDL-cholesterol, but only in unadjusted analyses that did not account for HPD use and other risk factors.CONCLUSION: No associations between ambient or at-the-ear occupational noise exposure and serum lipid levels were observed. This indicates that a causal pathway between occupational and residential noise exposure and cardiovascular disease does not include alteration of lipid levels.

AB - OBJECTIVES: Occupational and residential noise exposure has been related to increased risk of cardiovascular disease. Alteration of serum lipid levels has been proposed as a possible causal pathway. The objective of this study was to investigate the relation between ambient and at-the-ear occupational noise exposure and serum levels of total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, and triglycerides when accounting for well-established predictors of lipid levels.METHODS: This cross-sectional study included 424 industrial workers and 84 financial workers to obtain contrast in noise exposure levels. They provided a serum sample and wore portable dosimeters that every 5-s recorded ambient noise exposure levels during a 24-h period. We extracted measurements obtained during work and calculated the full-shift mean ambient noise level. For 331 workers who kept a diary on the use of a hearing protection device (HPD), we subtracted 10 dB from every noise recording obtained during HPD use and estimated the mean full-shift noise exposure level at the ear.RESULTS: Mean ambient noise level was 79.9 dB (A) [range 55.0-98.9] and the mean estimated level at the ear 77.8 dB (A) [range 55.0-94.2]. Ambient and at-the-ear noise levels were strongly associated with increasing levels of triglycerides, cholesterol-HDL ratio, and decreasing levels of HDL-cholesterol, but only in unadjusted analyses that did not account for HPD use and other risk factors.CONCLUSION: No associations between ambient or at-the-ear occupational noise exposure and serum lipid levels were observed. This indicates that a causal pathway between occupational and residential noise exposure and cardiovascular disease does not include alteration of lipid levels.

U2 - 10.1007/s00420-016-1145-3

DO - 10.1007/s00420-016-1145-3

M3 - Journal article

C2 - 27319006

SN - 0340-0131

VL - 89

SP - 1087

EP - 1093

JO - International Archives of Occupational and Environmental Health

JF - International Archives of Occupational and Environmental Health

IS - 7

ER -

Ambient and at-the-ear occupational noise exposure and serum lipid levels

Abstract

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