Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis

L Andresen; V.L. Jørgensen; A. Perner; A. Hansen; J Eugen-Olsen; Jørgen Rask-Madsen; L Andresen; V L Jørgensen; A Perner; A Hansen; J Rask-Madsen

doi:10.1136/gut.2003.034165

Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis

L Andresen, V.L. Jørgensen, A. Perner, A. Hansen, J Eugen-Olsen, Jørgen Rask-Madsen, L Andresen, V L Jørgensen, A Perner, A Hansen, J Rask-Madsen

138 Citations (Scopus)

Abstract

Expression of inducible nitric oxide synthase (iNOS) is greatly upregulated in the colonic mucosa of patients with collagenous and ulcerative colitis. As the transcription factor nuclear factor kappaB (NFkappaB) is a major inducer of iNOS gene expression, we compared activation and transcriptional activity of NFkappaB in colonic mucosal biopsies from these patients.

Original language	English
Journal	Gut
Volume	54
Issue number	4
Pages (from-to)	503-9
Number of pages	7
ISSN	0017-5749
DOIs	https://doi.org/10.1136/gut.2003.034165 https://doi.org/10.1136/gut.2003.034165
Publication status	Published - 2005

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Andresen, L., Jørgensen, V. L., Perner, A., Hansen, A., Eugen-Olsen, J., Rask-Madsen, J., Andresen, L., Jørgensen, V. L., Perner, A., Hansen, A., & Rask-Madsen, J. (2005). Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis. Gut, 54(4), 503-9. https://doi.org/10.1136/gut.2003.034165, https://doi.org/10.1136/gut.2003.034165

Andresen, L, Jørgensen, VL, Perner, A, Hansen, A, Eugen-Olsen, J, Rask-Madsen, J, Andresen, L, Jørgensen, VL, Perner, A, Hansen, A & Rask-Madsen, J 2005, 'Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis', Gut, vol. 54, no. 4, pp. 503-9. https://doi.org/10.1136/gut.2003.034165, https://doi.org/10.1136/gut.2003.034165

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abstract = "Expression of inducible nitric oxide synthase (iNOS) is greatly upregulated in the colonic mucosa of patients with collagenous and ulcerative colitis. As the transcription factor nuclear factor kappaB (NFkappaB) is a major inducer of iNOS gene expression, we compared activation and transcriptional activity of NFkappaB in colonic mucosal biopsies from these patients.",

author = "L Andresen and V.L. J{\o}rgensen and A. Perner and A. Hansen and J Eugen-Olsen and J{\o}rgen Rask-Madsen and L Andresen and J{\o}rgensen, {V L} and A Perner and A Hansen and J Rask-Madsen",

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AU - Andresen, L

AU - Jørgensen, V.L.

AU - Perner, A.

AU - Hansen, A.

AU - Eugen-Olsen, J

AU - Rask-Madsen, Jørgen

AU - Andresen, L

AU - Jørgensen, V L

AU - Perner, A

AU - Hansen, A

AU - Rask-Madsen, J

PY - 2005

Y1 - 2005

N2 - Expression of inducible nitric oxide synthase (iNOS) is greatly upregulated in the colonic mucosa of patients with collagenous and ulcerative colitis. As the transcription factor nuclear factor kappaB (NFkappaB) is a major inducer of iNOS gene expression, we compared activation and transcriptional activity of NFkappaB in colonic mucosal biopsies from these patients.

AB - Expression of inducible nitric oxide synthase (iNOS) is greatly upregulated in the colonic mucosa of patients with collagenous and ulcerative colitis. As the transcription factor nuclear factor kappaB (NFkappaB) is a major inducer of iNOS gene expression, we compared activation and transcriptional activity of NFkappaB in colonic mucosal biopsies from these patients.

U2 - 10.1136/gut.2003.034165

DO - 10.1136/gut.2003.034165

M3 - Journal article

C2 - 15753535

SN - 0017-5749

VL - 54

SP - 503

EP - 509

JO - Gut

JF - Gut

IS - 4

ER -

Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis

Abstract

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