A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning

TY - GEN

T1 - A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning

AU - Wang, Zhenyu

AU - Stangegaard, Michael

AU - Dufva, Hans Martin

AU - Kutter, Jörg P.

AU - Wolff, Anders

PY - 2005

Y1 - 2005

N2 - SU-8, an epoxy-based photoresist, widely used in constitution different mTAS systems, is incompatible with mammalian cell adhesion and culture in its native form. Here, we demonstrate a simple, cheap and robust two-step method to render a SU-8 surface hydrophilic and compatible with cell culture. The contact angle of SU-8 surface was significantly reduced from 90° to 25° after the surface modification. The treated SU-8 surfaces provided a cell culture environment that was comparable with cell culture flask surface in terms of generation time and morphology.

AB - SU-8, an epoxy-based photoresist, widely used in constitution different mTAS systems, is incompatible with mammalian cell adhesion and culture in its native form. Here, we demonstrate a simple, cheap and robust two-step method to render a SU-8 surface hydrophilic and compatible with cell culture. The contact angle of SU-8 surface was significantly reduced from 90° to 25° after the surface modification. The treated SU-8 surfaces provided a cell culture environment that was comparable with cell culture flask surface in terms of generation time and morphology.

M3 - Article in proceedings

SP - 745

EP - 747

BT - Proceedings of MicroTAS 2005

T2 - Micro Total Analysis Systems (µTAS) 2005

Y2 - 9 October 2006 through 13 October 2006

ER -