Korbinian Löbmann

Research output

Research output per year 2011 2015 2016 2017 2018 2019 2019

• 81 Journal article
• 1 Book chapter
• 1 Conference abstract in journal
• 1 Editorial
• 2 More
  • 1 Review
  • 1 Net publication - Internet publication

Research output per year

Research output per year

Search results

• 2016

  Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling

  Lim, A. W., Löbmann, K., Grohganz, H., Rades, T. & Chieng, N., 1 Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Naproxen 100%
  • Cimetidine 91%
  • Ball Milling 79%
  • Indomethacin 76%
  • Cooling 67%
  34 Citations (Scopus)

• Preparation and characterization of spray-dried co-amorphous drug-amino acid salts

  Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, H., Kleinebudde, P., Rades, T. & Löbmann, K., 1 May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Acid Salt 100%
  • Indomethacin 84%
  • Salts 75%
  • Dissolution 63%
  • Amino Acids 59%
  63 Citations (Scopus)

• Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin

  Beyer, A., Radi, L., Grohganz, H., Löbmann, K., Rades, T. & Leopold, C. S., 1 Jul 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 104, p. 72-81 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Naproxen 100%
  • Indomethacin 76%
  • Amorphous Material 53%
  • Powder X-Ray Diffractometry 33%
  • Pharmaceutical Preparations 31%
  23 Citations (Scopus)

• Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage

  Sovago, I., Wang, W., Qiu, D., Raijada, D. K., Rantanen, J., Grohganz, H., Rades, T., Bond, A. D. & Löbmann, K., Apr 2016, In: Molecules. 21, 4, p. 1-13 13 p., 509.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Naproxen Sodium 100%
  • lactose 87%
  • Naproxen 76%
  • Lactose 69%
  • sodium 52%
  10 Citations (Scopus)

• Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development

  Knopp, M. M., Löbmann, K., Elder, D. P., Rades, T. & Holm, R., 25 May 2016, In: European Journal of Pharmaceutical Sciences. 87, p. 164-173 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Differential Scanning Calorimetry 100%
  • Drug Development 77%
  • Pharmaceutical Preparations 13%
  • Hot Temperature 12%
  32 Citations (Scopus)

• Recent advances in co-amorphous drug formulations

  Dengale, S. J., Grohganz, H., Rades, T. & Löbmann, K., 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 116-125 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Drug Compounding 100%
  • Molecular Weight 71%
  • Amorphous Material 59%
  • Drug 45%
  • Dissolution 42%
  201 Citations (Scopus)

• Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems

  Svagan, A. J., Benjamins, J-W., Al-Ansari, Z., Shalom, D. B., Müllertz, A., Wågberg, L. & Löbmann, K., 28 Dec 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Nanofibers 100%
  • Cellulose 92%
  • Drug Delivery Systems 75%
  • Foam 69%
  • Nanofiber 65%
  34 Citations (Scopus)

• Solvent free amorphisation for pediatric formulations (minitablets) using mesoporous silica

  Monsuur, F., Choudhari, Y., Reddy, U., McCarthy, W., Sadek, I., Grohganz, H., Rades, T. & Löbmann, K., 25 Sept 2016, In: International Journal of Pharmaceutics. 511, 2, p. 1135-1136

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• The influence of co-formers on the dissolution rates of co-amorphous sulfamerazine/excipient systems

  Gniado, K., Löbmann, K., Rades, T. & Erxleben, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 20-6 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Sulfamerazine 100%
  • Excipients 60%
  • Excipient 56%
  • Dissolution 38%
  • Powders 26%
  13 Citations (Scopus)
• 2015

  Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying

  Craye, G., Löbmann, K., Grohganz, H., Rades, T. & Laitinen, R., 3 Dec 2015, In: Molecules. 20, 12, p. 21532-48 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Simvastatin 100%
  • sodium sulfates 75%
  • Sodium Dodecyl Sulfate 73%
  • drying 67%
  • Spray 63%
  29 Citations (Scopus)

• Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility

  Knopp, M. M., Tajber, L., Tian, Y., Olesen, N. E., Jones, D. S., Kozyra, A., Löbmann, K., Paluch, K., Brennan, C. M., Holm, R., Healy, A. M., Andrews, G. P. & Rades, T., 8 Sept 2015, In: Molecular Pharmaceutics. 12, 9, p. 3408-19 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Solubility 100%
  • Polymers 88%
  • vinyl acetate 53%
  • Pharmaceutical Preparations 41%
  • Vinyl Acetate 40%
  67 Citations (Scopus)

• Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media

  Heikkinen, A. T., DeClerck, L., Löbmann, K., Grohganz, H., Rades, T. & Laitinen, R., 1 Jul 2015, In: Pharmazie. 70, 7, p. 452-457 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Buffers 100%
  • Dissolution 80%
  • Amino Acids 76%
  • Buffer Solution 69%
  • Pharmaceutical Preparations 44%
  15 Citations (Scopus)

• Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

  Sassene, P. J., Mosgaard, M. D., Löbmann, K., Mu, H., Larsen, F. H., Rades, T. & Müllertz, A., 22 Sept 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cinnarizine 100%
  • Drug Delivery Systems 59%
  • Pellet 41%
  • Lipids 39%
  • Drug 31%
  25 Citations (Scopus)

• Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques

  Knopp, M. M., Olesen, N. E., Holm, P., Löbmann, K., Holm, R., Langguth, P. & Rades, T., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 44-51 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Drug Evaluation 100%
  • Solubility 80%
  • Casting 71%
  • Polymers 71%
  • Spray 56%
  27 Citations (Scopus)

• Formation mechanism of coamorphous drug−amino acid mixtures

  Jensen, K. B. T., Larsen, F. H., Cornett, C., Löbmann, K., Grohganz, H. & Rades, T., 6 Jul 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Acids 100%
  • Amorphization 98%
  • Amino Acids 77%
  • Drug 69%
  • Powders 66%
  51 Citations (Scopus)

• Improvement of dissolution rate of indomethacin by inkjet printing.

  Wickström, H., Palo, M., Rijckaert, K., Kolakovic, R., Nyman, J. O., Määttänen, A., Ihalainen, P., Peltonen, J., Genina, N., de Beer, T., Löbmann, K., Rades, T. & Sandler, N., 30 Jul 2015, In: European Journal of Pharmaceutical Sciences. 75, p. 91–100 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Printing 100%
  • Ink 78%
  • Indomethacin 77%
  • Excipients 45%
  • Arginine 35%
  45 Citations (Scopus)

• Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin

  Beyer, A., Grohganz, H., Löbmann, K., Rades, T. & Leopold, C. S., 27 Oct 2015, In: Molecules. 20, 10, p. 19571-87 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Powder X-Ray Diffractometry 100%
  • Naproxen 99%
  • Powders 77%
  • Indomethacin 76%
  • X-Rays 59%
  7 Citations (Scopus)

• Predicting Crystallization of Amorphous Drugs with Terahertz Spectroscopy

  Sibik, J., Löbmann, K., Rades, T. & Zeitler, J. A., 3 Aug 2015, In: Molecular Pharmaceutics. 12, 8, p. 3062-68 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Terahertz Spectroscopy 100%
  • Crystallization 60%
  • Molecular Dynamics Simulation 41%
  • Transition Temperature 34%
  • Amorphous Material 34%
  71 Citations (Scopus)

• Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin-arginine

  Lenz, E., Jensen, K. B. T., Blaabjerg, L. I., Knop, K., Grohganz, H., Löbmann, K., Rades, T. & Kleinebudde, P., 25 Jul 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 96, p. 44–52 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Indomethacin 100%
  • Spray 94%
  • Arginine 92%
  • Tablets 92%
  • Dissolution 74%
  46 Citations (Scopus)
• 2014

  Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability

  Laitinen, R., Löbmann, K., Grohganz, H., Strachan, C. & Rades, T., 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Simvastatin 100%
  • Glyburide 80%
  • Excipients 79%
  • Excipient 74%
  • Amino Acids 47%
  68 Citations (Scopus)

• Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers

  Löbmann, K., Laitinen, R., Grohganz, H. & Rades, T., 2014, In: CRS Newsletter. 31, 3, p. 16-17

  Research output: Contribution to journal › Journal article › Communication

• Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid proline

  Jensen, K. B. T., Löbmann, K., Rades, T. & Grohganz, H., 14 Jul 2014, In: Pharmaceutics. 6, 3, p. 416-435 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Drug Compounding 100%
  • Proline 91%
  • Naproxen 79%
  • Water Soluble 66%
  • Amino Acids 60%
  70 Citations (Scopus)

• Refining stability and dissolution rate of amorphous drug formulations

  Grohganz, H., Priemel, P. A., Löbmann, K., Nielsen, L. H., Laitinen, R., Mullertz, A., Van den Mooter, G. & Rades, T., Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Drug Compounding 100%
  • Dissolution 63%
  • Amorphous Material 59%
  • Drug 45%
  • Pharmaceutical 42%
  90 Citations (Scopus)

• Stabilized amorphous solid dispersions with small molecule excipients

  Löbmann, K., Jensen, K. B. T., Laitinen, R., Rades, T., Strachan, C. & Grohganz, H., 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 613-626 24 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  • molecules 100%

• The influence of pressure on the intrinsic dissolution rate of amorphous indomethacin

  Löbmann, K., Flouda, K., Qiu, D., Tsolakou, T., Wang, W. & Rades, T., 2014, In: Pharmaceutics. 6, 3, p. 481-493 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• The influence of pressure on the intrinsic dissolution rate of amorphous indomethacin

  Löbmann, K., Flouda, K., Qiu, D., Tsolakou, T., Wang, W. & Rades, T., 20 Aug 2014, In: Pharmaceutics. 6, 3, p. 481-93 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Indomethacin 100%
  • Dissolution 74%
  • Amorphous Material 69%
  • Pressure 65%
  • Surface Properties 53%
  14 Citations (Scopus)
• 2013

  Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement

  Löbmann, K., Grohganz, H., Laitinen, R., Strachan, C. & Rades, T., Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Water Soluble 100%
  • Dissolution 96%
  • Amino Acids 91%
  • Water 86%
  • Drug 68%
  174 Citations (Scopus)

• Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions

  Löbmann, K., Laitinen, R., Strachan, C., Rades, T. & Grohganz, H., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 882-888

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Water Soluble 100%
  • Amino Acids 91%
  • Water 86%
  • Drug 68%
  • Pharmaceutical Preparations 54%
  103 Citations (Scopus)

• Amorphous drugs and dosage forms

  Grohganz, H., Löbmann, K., Priemel, P., Jensen, K. B. T., Graeser, K., Strachan, C. & Rades, T., 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 403-408 6 p.

  Research output: Contribution to journal › Review

  • Dosage Forms 100%
  • Dosage Form 90%
  • Amorphous Material 61%
  • Drug 46%
  • Pharmaceutical Preparations 36%
  36 Citations (Scopus)

• A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin

  Löbmann, K., Laitinen, R., Grohganz, H., Strachan, C. J., Rades, T. & Gordon, K. C., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 80-87 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Naproxen 100%
  • Indomethacin 76%
  • Theoretical Models 62%
  • Drug 40%
  • Amorphous Material 33%
  77 Citations (Scopus)

• Co-amorphous drug-delivery systems

  Löbmann, K., 2013

  Research output: Other contribution › Net publication - Internet publication › Communication

• Emerging trends in the stabilization of amorphous drugs

  Laitinen, R., Löbmann, K., Strachan, C. J., Grohganz, H. & Rades, T., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 65-79 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Amorphous Material 100%
  • Drug 76%
  • Pharmaceutical Preparations 60%
  • Solubility 58%
  • Polymers 51%
  271 Citations (Scopus)
• 2012

  Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

  Löbmann, K., Strachan, C., Grohganz, H., Rades, T., Korhonen, O. & Laitinen, R., May 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 1, p. 159-69 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Glipizide 100%
  • Simvastatin 89%
  • Intermolecular Force 53%
  • Mixture 26%
  • Drug Combinations 21%
  148 Citations (Scopus)

• Ordnung muss (nicht) sein

  Löbmann, K. A. M., Jensen, K. B. T., Grohganz, H. & Rades, T., 2012, In: Lægemiddelforskning. 2012, p. 34-36

  Research output: Contribution to journal › Journal article › Communication
• 2011

  Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen

  Löbmann, K., Laitinen, R., Grohganz, H., Gordon, K. C., Strachan, C. & Rades, T., 3 Oct 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Naproxen 100%
  • Indomethacin 76%
  • Dissolution 57%
  • Drug 40%
  • Pharmaceutical Preparations 31%
  233 Citations (Scopus)

• Investigation of the formation process of two piracetam cocrystals during grinding

  Rehder, S., Klukkert, M., Löbmann, K., Strachan, C. J., Sakmann, A., Gordon, K., Rades, T. & Leopold, C. S., Dec 2011, In: Pharmaceutics. 3, 4, p. 706-722 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Piracetam 100%
  • tartaric acid 25%
  • Raman Spectroscopy 22%
  • Raman Spectrum Analysis 22%
  • Acid 21%
  45 Citations (Scopus)