Abstract
Severe sepsis is a leading cause of death characterised by infection-induced endothelial and cardiac dysfunction leading to hypovolaemia, maldistribution of flow, tissue ischaemia and organ failure. A clinical approach with focus on cardiovascular diagnostics and rational goal-directed therapy is likely to reduce the high mortality. The treatment involves focus control, broad-spectrum antibiotics, target-oriented fluid therapy and vasopressor and inotropic agents guided by frequent reassessments of the patient's response to treatment.
Bidragets oversatte titel | [Early identification and treatment of cardiovascular failure in severe sepsis] |
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Originalsprog | Dansk |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 172 |
Udgave nummer | 3 |
Sider (fra-til) | 210-4 |
Antal sider | 5 |
ISSN | 0041-5782 |
Status | Udgivet - 18 jan. 2010 |