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The VICM biomarker is released from activated macrophages and inhibited by anti-GM-CSFR alpha-mAb treatment in rheumatoid arthritis patients
J. Mortensen, X. Guo, M. De Los Reyes,
M. Dziegiel
, M. Karsdal, A. Bay-Jensen, W. White
Institut for Klinisk Medicin
7
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Medicin og biovidenskab
Acute Disease
8%
Biomarkers
35%
Blood Cells
6%
Calcium Chloride
10%
Chronic Disease
5%
Citrullination
12%
Enzyme-Linked Immunosorbent Assay
5%
Gene Expression
4%
Granulocyte-Macrophage Colony-Stimulating Factor
8%
In Vitro Techniques
3%
Joints
11%
Lipopolysaccharides
6%
Macrophages
38%
Matrix Metalloproteinase 9
8%
Matrix Metalloproteinases
7%
mavrilimumab
100%
Methotrexate
15%
Protein-Arginine Deiminases
25%
Reverse Transcriptase Polymerase Chain Reaction
7%
Rheumatoid Arthritis
45%
Serum
10%
Therapeutics
8%
Vimentin
16%
Western Blotting
10%