The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes

Medicin og biovidenskab

• 7 alpha-hydroxy-4-cholesten-3-one 16%
• Appetite 9%
• Area Under Curve 7%
• Bile 8%
• Bile Acids and Salts 65%
• Cholecystokinin 31%
• cholecystokinin 8 13%
• Cross-Over Studies 8%
• Eating 6%
• Energy Metabolism 8%
• Enteroendocrine Cells 25%
• Fibroblast Growth Factor 7 13%
• G-Protein-Coupled Receptors 18%
• Gallbladder 9%
• Gallbladder Emptying 14%
• Gastric Emptying 10%
• Glucagon-Like Peptide 1 74%
• Glucose 11%
• Insulin 6%
• Intravenous Infusions 8%
• L Cells 23%
• Metformin 9%
• Placebos 12%
• Sevelamer 100%
• Triglycerides 7%
• Type 2 Diabetes Mellitus 47%