Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957

Medicin og biovidenskab

• Amphetamine 5%
• Animals 2%
• Brain 4%
• Cerebellum 8%
• Corpus Striatum 4%
• Dopamine 12%
• Dopamine Agonists 5%
• Dopamine Antagonists 5%
• Dopamine D1 Receptors 18%
• Dopamine Uptake Inhibitors 7%
• Guaiacol 65%
• High Pressure Liquid Chromatography 4%
• Metabolic Networks and Pathways 4%
• Mixed Function Oxygenases 5%
• Pharmacology 3%
• RTI-COC 32 11%
• SCH 23390 12%
• Sensitivity and Specificity 3%
• SKF 82957 100%
• Tolcapone 24%
• Transferases 44%
• Tyrosine 4%