Synovial volume--a marker of disease severity in rheumatoid arthritis? Quantification by MRI.

Mikkel Østergaard; P Gideon; O Henriksen; I Lorenzen

Synovial volume--a marker of disease severity in rheumatoid arthritis? Quantification by MRI.

Bidragets oversatte titel: Synovial volume--a marker of disease severity in rheumatoid arthritis? Quantification by MRI.

Mikkel Østergaard, P Gideon, O Henriksen, I Lorenzen

75 Citationer (Scopus)

Abstract

Volumes of synovial membrane and joint effusion were determined by magnetic resonance imaging (MRI) in patients with inflammatory gonarthritis. Volumes were calculated by adding the outlined areas of synovium/effusion from a continuous series of gadolinium-DTPA-enhanced 5 mm transversal T1-weighted MR-images. Ten knees with clinically active gonarthritis (CAG), 8 knees with clinically inactive gonarthritis (CIG) and 5 healthy controls (HC) were examined. The synovial volume of CAG-, CIG- and HC-knees were significantly different. The median volumes were 79 ml, 21 ml and 3 ml, respectively. Synovial and effusion volumes were highly correlated. A selected sagittal one-slice volume showed a high correlation to the total volumes. The reliable quantification of synovial and effusion volumes could be useful in the assessment of disease severity and as an outcome measure to treatment.

Bidragets oversatte titel	Synovial volume--a marker of disease severity in rheumatoid arthritis? Quantification by MRI.
Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Rheumatology
Vol/bind	23
Udgave nummer	4
Sider (fra-til)	197-202
Antal sider	6
ISSN	0300-9742
Status	Udgivet - 1994

Adgang til dokumentet

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8091145&query_hl=243

Citationsformater

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title = "Synovial volume--a marker of disease severity in rheumatoid arthritis? Quantification by MRI.",

abstract = "Volumes of synovial membrane and joint effusion were determined by magnetic resonance imaging (MRI) in patients with inflammatory gonarthritis. Volumes were calculated by adding the outlined areas of synovium/effusion from a continuous series of gadolinium-DTPA-enhanced 5 mm transversal T1-weighted MR-images. Ten knees with clinically active gonarthritis (CAG), 8 knees with clinically inactive gonarthritis (CIG) and 5 healthy controls (HC) were examined. The synovial volume of CAG-, CIG- and HC-knees were significantly different. The median volumes were 79 ml, 21 ml and 3 ml, respectively. Synovial and effusion volumes were highly correlated. A selected sagittal one-slice volume showed a high correlation to the total volumes. The reliable quantification of synovial and effusion volumes could be useful in the assessment of disease severity and as an outcome measure to treatment.",

author = "Mikkel {\O}stergaard and P Gideon and O Henriksen and I Lorenzen",

year = "1994",

language = "English",

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pages = "197--202",

journal = "Scandinavian Journal of Rheumatology",

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TY - JOUR

T1 - Synovial volume--a marker of disease severity in rheumatoid arthritis? Quantification by MRI.

AU - Østergaard, Mikkel

AU - Gideon, P

AU - Henriksen, O

AU - Lorenzen, I

PY - 1994

Y1 - 1994

N2 - Volumes of synovial membrane and joint effusion were determined by magnetic resonance imaging (MRI) in patients with inflammatory gonarthritis. Volumes were calculated by adding the outlined areas of synovium/effusion from a continuous series of gadolinium-DTPA-enhanced 5 mm transversal T1-weighted MR-images. Ten knees with clinically active gonarthritis (CAG), 8 knees with clinically inactive gonarthritis (CIG) and 5 healthy controls (HC) were examined. The synovial volume of CAG-, CIG- and HC-knees were significantly different. The median volumes were 79 ml, 21 ml and 3 ml, respectively. Synovial and effusion volumes were highly correlated. A selected sagittal one-slice volume showed a high correlation to the total volumes. The reliable quantification of synovial and effusion volumes could be useful in the assessment of disease severity and as an outcome measure to treatment.

AB - Volumes of synovial membrane and joint effusion were determined by magnetic resonance imaging (MRI) in patients with inflammatory gonarthritis. Volumes were calculated by adding the outlined areas of synovium/effusion from a continuous series of gadolinium-DTPA-enhanced 5 mm transversal T1-weighted MR-images. Ten knees with clinically active gonarthritis (CAG), 8 knees with clinically inactive gonarthritis (CIG) and 5 healthy controls (HC) were examined. The synovial volume of CAG-, CIG- and HC-knees were significantly different. The median volumes were 79 ml, 21 ml and 3 ml, respectively. Synovial and effusion volumes were highly correlated. A selected sagittal one-slice volume showed a high correlation to the total volumes. The reliable quantification of synovial and effusion volumes could be useful in the assessment of disease severity and as an outcome measure to treatment.

M3 - Journal article

SN - 0300-9742

VL - 23

SP - 197

EP - 202

JO - Scandinavian Journal of Rheumatology

JF - Scandinavian Journal of Rheumatology

IS - 4

ER -