TY - JOUR
T1 - Sinonasal inflammation in COPD
T2 - a systematic review
AU - Håkansson, Kåre
AU - Konge, Lars
AU - Thomsen, Sf
AU - Backer, V
AU - Buchwald, Christian von
PY - 2013/11/1
Y1 - 2013/11/1
N2 - In this review, we demonstrate that patients with chronic obstructive pulmonary disease (COPD) frequently report sinonasal symptoms. Furthermore, we present evidence that smoking on its own can cause nasal disease and that, in COPD patients, nasal inflammation mimics that of the bronchi. All this evidence suggests that COPD-related sinonasal disease does exist and that smoking on its own rather than systemic inflammation triggers the condition. However, COPD-related sinonasal disease remains to be characterised in terms of symptoms and endoscopic findings. In addition, more studies are needed to quantify the negative impact of sinonasal symptoms on the quality of life in COPD patients.
AB - In this review, we demonstrate that patients with chronic obstructive pulmonary disease (COPD) frequently report sinonasal symptoms. Furthermore, we present evidence that smoking on its own can cause nasal disease and that, in COPD patients, nasal inflammation mimics that of the bronchi. All this evidence suggests that COPD-related sinonasal disease does exist and that smoking on its own rather than systemic inflammation triggers the condition. However, COPD-related sinonasal disease remains to be characterised in terms of symptoms and endoscopic findings. In addition, more studies are needed to quantify the negative impact of sinonasal symptoms on the quality of life in COPD patients.
U2 - 10.1183/09031936.00119712
DO - 10.1183/09031936.00119712
M3 - Journal article
C2 - 23100505
SN - 0904-1850
JO - Acta tuberculosea Scandinavica
JF - Acta tuberculosea Scandinavica
ER -