Abstract
Biochemical assessment of gonadal function during maturation in girls and in adult women can be troublesome. With the recent advent of specific assays for the gonadal peptides inhibin A and inhibin B, it might be possible to achieve a clearer picture of events. We therefore determined serum levels of inhibin A, inhibin B, FSH, LH and estradiol in a cross-sectional study of 403 healthy schoolgirls (aged 6 -20 yr) in relation to age and stage of puberty and in 181 healthy nonpregnant women (aged 20-32 yr) in relation to stage of the menstrual cycle. In addition, inhibin A and inhibin B were measured daily throughout the menstrual cycle in 10 healthy adult women. Levels of inhibin B are low or undetectable in prepubertal girls (median, 26.5 pg/mL; 95% prediction interval,
Originalsprog | Engelsk |
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Tidsskrift | Journal of Clinical Endocrinology and Metabolism |
Vol/bind | 85 |
Udgave nummer | 4 |
Sider (fra-til) | 1634-40 |
Antal sider | 7 |
ISSN | 0021-972X |
Status | Udgivet - 2000 |