Pharmacology of a constitutively active muscarinic receptor generated by random mutagenesis

Medicin og biovidenskab

• (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride 75%
• Arecoline 70%
• Atropine 46%
• Binding Sites 35%
• Carbachol 51%
• clidinium 96%
• G-Protein-Coupled Receptors 45%
• Libraries 40%
• Ligands 64%
• Muscarinic M5 Receptors 80%
• Muscarinic Receptors 100%
• Mutagenesis 90%
• Mutation 51%
• N-methylpiperidine 84%
• Pharmacology 60%
• Pirenzepine 63%
• Proline 48%
• Scopolamine 55%
• Serine 44%
• Threonine 51%
• Tyrosine 42%