Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis

TY - JOUR

T1 - Perceived job insecurity as a risk factor for incident coronary heart disease

T2 - systematic review and meta-analysis

AU - Virtanen, Marianna

AU - Nyberg, Solja T

AU - Batty, George David

AU - Jokela, Markus

AU - Heikkilä, Katriina

AU - Fransson, Eleonor I

AU - Alfredsson, Lars

AU - Bjorner, Jakob B

AU - Borritz, Marianne

AU - Burr, Hermann

AU - Casini, Annalisa

AU - Clays, Els

AU - De Bacquer, Dirk

AU - Dragano, Nico

AU - Elovainio, Marko

AU - Erbel, Raimund

AU - Ferrie, Jane E

AU - Hamer, Mark

AU - Jöckel, Karl-Heinz

AU - Kittel, France

AU - Knutsson, Anders

AU - Koskenvuo, Markku

AU - Koskinen, Aki

AU - Lunau, Thorsten

AU - Madsen, Ida Elisabeth Huitfeldt

AU - Nielsen, Martin L

AU - Nordin, Maria

AU - Oksanen, Tuula

AU - Pahkin, Krista

AU - Pejtersen, Jan

AU - Pentti, Jaana

AU - Rugulies, Reiner Ernst

AU - Salo, Paula

AU - Shipley, Martin J

AU - Siegrist, Johannes

AU - Steptoe, Andrew

AU - Suominen, Sakari B

AU - Theorell, Töres

AU - Toppinen-Tanner, Salla

AU - Väänänen, Ari

AU - Vahtera, Jussi

AU - Westerholm, Peter J M

AU - Westerlund, Hugo

AU - Slopen, Natalie

AU - Kawachi, Ichiro

AU - Singh-Manoux, Archana

AU - Kivimäki, Mika

AU - Consortium, IPD-Work

PY - 2013/8/17

Y1 - 2013/8/17

N2 - Objective To determine the association between self reported job insecurity and incident coronary heart disease. Design A meta-analysis combining individual level data from a collaborative consortium and published studies identified by a systematic review. Data sources We obtained individual level data from 13 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. Four published prospective cohort studies were identified by searches of Medline (to August 2012) and Embase databases (to October 2012), supplemented by manual searches. Review methods Prospective cohort studies that reported risk estimates for clinically verified incident coronary heart disease by the level of self reported job insecurity. Two independent reviewers extracted published data. Summary estimates of association were obtained using random effects models. Results The literature search yielded four cohort studies. Together with 13 cohort studies with individual participant data, the meta-analysis comprised up to 174 438 participants with a mean follow-up of 9.7 years and 1892 incident cases of coronary heart disease. Age adjusted relative risk of high versus low job insecurity was 1.32 (95% confidence interval 1.09 to 1.59). The relative risk of job insecurity adjusted for sociodemographic and risk factors was 1.19 (1.00 to 1.42). There was no evidence of significant differences in this association by sex, age (<50 v =50 years), national unemployment rate, welfare regime, or job insecurity measure. Conclusions The modest association between perceived job insecurity and incident coronary heart disease is partly attributable to poorer socioeconomic circumstances and less favourable risk factor profiles among people with job insecurity.

AB - Objective To determine the association between self reported job insecurity and incident coronary heart disease. Design A meta-analysis combining individual level data from a collaborative consortium and published studies identified by a systematic review. Data sources We obtained individual level data from 13 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. Four published prospective cohort studies were identified by searches of Medline (to August 2012) and Embase databases (to October 2012), supplemented by manual searches. Review methods Prospective cohort studies that reported risk estimates for clinically verified incident coronary heart disease by the level of self reported job insecurity. Two independent reviewers extracted published data. Summary estimates of association were obtained using random effects models. Results The literature search yielded four cohort studies. Together with 13 cohort studies with individual participant data, the meta-analysis comprised up to 174 438 participants with a mean follow-up of 9.7 years and 1892 incident cases of coronary heart disease. Age adjusted relative risk of high versus low job insecurity was 1.32 (95% confidence interval 1.09 to 1.59). The relative risk of job insecurity adjusted for sociodemographic and risk factors was 1.19 (1.00 to 1.42). There was no evidence of significant differences in this association by sex, age (<50 v =50 years), national unemployment rate, welfare regime, or job insecurity measure. Conclusions The modest association between perceived job insecurity and incident coronary heart disease is partly attributable to poorer socioeconomic circumstances and less favourable risk factor profiles among people with job insecurity.

U2 - 10.1136/bmj.f4746

DO - 10.1136/bmj.f4746

M3 - Journal article

SN - 0959-8146

VL - 347

SP - 1

EP - 16

JO - BMJ

JF - BMJ

M1 - f4746

ER -