Oxidants and antioxidants in disease: oxidative stress in farm animals

Jens Lykkesfeldt; Ove Svendsen

doi:10.1016/j.tvjl.2006.06.005

Oxidants and antioxidants in disease: oxidative stress in farm animals

439 Citationer (Scopus)

Abstract

Important infectious diseases in farm animals, such as pneumonia and enteritis, are thought to be associated with the so-called oxidative stress, i.e. a chemical phenomenon involving an imbalance in the redox status of the individual animal. The specifics of oxidative stress and how it may result in disease or be prevented are complex questions with no simple answers. However, the considerable literature on the subject suggests that many researchers consider oxidative stress-related mechanisms to be important early events in disease development. A particularly intriguing aspect is that, at least theoretically, oxidative stress should be easily prevented with antioxidants yet the use of antioxidants as therapy remains controversial. The present knowledge on oxidative stress in farm animals is the topic of this review.

Originalsprog	Engelsk
Tidsskrift	Veterinary Journal
Vol/bind	173
Udgave nummer	3
Sider (fra-til)	502-511
Antal sider	10
ISSN	1090-0233
DOI	https://doi.org/10.1016/j.tvjl.2006.06.005
Status	Udgivet - 2007

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10.1016/j.tvjl.2006.06.005

Citationsformater

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title = "Oxidants and antioxidants in disease: oxidative stress in farm animals",

abstract = "Important infectious diseases in farm animals, such as pneumonia and enteritis, are thought to be associated with the so-called oxidative stress, i.e. a chemical phenomenon involving an imbalance in the redox status of the individual animal. The specifics of oxidative stress and how it may result in disease or be prevented are complex questions with no simple answers. However, the considerable literature on the subject suggests that many researchers consider oxidative stress-related mechanisms to be important early events in disease development. A particularly intriguing aspect is that, at least theoretically, oxidative stress should be easily prevented with antioxidants yet the use of antioxidants as therapy remains controversial. The present knowledge on oxidative stress in farm animals is the topic of this review.",

author = "Jens Lykkesfeldt and Ove Svendsen",

year = "2007",

doi = "10.1016/j.tvjl.2006.06.005",

language = "English",

volume = "173",

pages = "502--511",

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T1 - Oxidants and antioxidants in disease

T2 - oxidative stress in farm animals

AU - Lykkesfeldt, Jens

AU - Svendsen, Ove

PY - 2007

Y1 - 2007

N2 - Important infectious diseases in farm animals, such as pneumonia and enteritis, are thought to be associated with the so-called oxidative stress, i.e. a chemical phenomenon involving an imbalance in the redox status of the individual animal. The specifics of oxidative stress and how it may result in disease or be prevented are complex questions with no simple answers. However, the considerable literature on the subject suggests that many researchers consider oxidative stress-related mechanisms to be important early events in disease development. A particularly intriguing aspect is that, at least theoretically, oxidative stress should be easily prevented with antioxidants yet the use of antioxidants as therapy remains controversial. The present knowledge on oxidative stress in farm animals is the topic of this review.

AB - Important infectious diseases in farm animals, such as pneumonia and enteritis, are thought to be associated with the so-called oxidative stress, i.e. a chemical phenomenon involving an imbalance in the redox status of the individual animal. The specifics of oxidative stress and how it may result in disease or be prevented are complex questions with no simple answers. However, the considerable literature on the subject suggests that many researchers consider oxidative stress-related mechanisms to be important early events in disease development. A particularly intriguing aspect is that, at least theoretically, oxidative stress should be easily prevented with antioxidants yet the use of antioxidants as therapy remains controversial. The present knowledge on oxidative stress in farm animals is the topic of this review.

U2 - 10.1016/j.tvjl.2006.06.005

DO - 10.1016/j.tvjl.2006.06.005

M3 - Journal article

SN - 1090-0233

VL - 173

SP - 502

EP - 511

JO - The Veterinary Journal

JF - The Veterinary Journal

IS - 3

ER -

Oxidants and antioxidants in disease: oxidative stress in farm animals

Abstract

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