@article{1bbdf8d0b470415699992306d383f909,
title = "Nectin-1 binds and signals through the fibroblast growth factor receptor",
abstract = "Background: Nectin-1 is a cell-adhesion molecule important for the formation of synapses. Results: The third Ig module of nectin-1 (nectin-1 Ig3) induces neuronal differentiation and promotes neuronal survival through a direct interaction with FGF receptor. Conclusion: FGF receptor is a downstream signaling partner of nectin-1. Significance: This mechanism of nectin-1 signaling is crucial for understanding its neuritogenic and survival promoting effects.",
keywords = "Amino Acid Sequence, Animals, Apoptosis, Cell Adhesion Molecules, Cell Survival, Crystallography, X-Ray, Fibroblast Growth Factor 2, HEK293 Cells, Hippocampus, Humans, Mice, Molecular Sequence Data, Neurites, Neurons, Phosphorylation, Primary Cell Culture, Protein Binding, Protein Isoforms, Protein Processing, Post-Translational, Protein Structure, Secondary, Protein Structure, Tertiary, Rats, Rats, Wistar, Receptor, Fibroblast Growth Factor, Type 1, Receptors, Platelet-Derived Growth Factor, Signal Transduction, Surface Plasmon Resonance",
author = "Bojesen, {Kirsten Borup} and Ole Clausen and Kristian Rohde and Claus Christensen and Lanjun Zhang and Shizhong Li and K{\o}hler, {Lene Boding} and Steen Nielbo and Janne Nielsen and Gj{\o}rlund, {Michelle Denise} and Poulsen, {Flemming Martin} and Bock, {Elisabeth Marianne} and Vladimir Berezin",
year = "2012",
month = oct,
day = "26",
doi = "10.1074/jbc.M112.345215",
language = "English",
volume = "287",
pages = "37420--37433",
journal = "Journal of Biological Chemistry",
issn = "0021-9258",
publisher = "American Society for Biochemistry and Molecular Biology, Inc.",
number = "44",
}