Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation.

Medicin og biovidenskab

• Activating Transcription Factor 2 100%
• U937 Cells 78%
• Cyclic AMP Response Element-Binding Protein 78%
• NF-kappa B 66%
• Helicobacter pylori 60%
• Interleukin-8 59%
• p38 Mitogen-Activated Protein Kinases 19%
• Transcription Factor AP-1 13%
• NF-KappaB Inhibitor alpha 11%
• 3-(4-methylphenylsulfonyl)-2-propenenitrile 9%
• 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole 9%
• 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester 8%
• Dantrolene 8%
• SB 203580 7%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 7%
• Chelating Agents 6%
• Cyclooxygenase 2 6%
• Small Interfering RNA 5%
• Interleukin-6 4%
• Transcription Factors 4%
• Growth 3%