Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

Medicin og biovidenskab

• 1-(((2-((5-cyanopyridin-2-yl)amino)ethyl)amino)acetyl)-2-cyano-(S)-pyrrolidine 100%
• Animals 7%
• Area Under Curve 5%
• Body Weight 5%
• Diet 15%
• Dipeptidyl Peptidase 4 79%
• Dipeptidyl-Peptidase IV Inhibitors 9%
• Drinking Water 7%
• Enzymes 4%
• Facilitative Glucose Transport Proteins 17%
• Fats 11%
• Glucagon 7%
• Glucagon-Like Peptide 1 17%
• Glucose 37%
• High Fat Diet 36%
• Immunohistochemistry 5%
• Inbred C57BL Mouse 6%
• Insulin 15%
• Insulin Resistance 6%
• Insulin Secretion 14%
• Protein Isoforms 11%
• Stomach 5%
• Therapeutics 3%