Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency

TY - JOUR

T1 - Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency

AU - Gynthersen, Rosa

AU - Qvist, Tavs

AU - Andersen, Åse B.

AU - Katzenstein, Terese L.

PY - 2019/2/1

Y1 - 2019/2/1

N2 - Mycobacterium brisbanense is rapid-growing nontuberculous mycobacteria. It was first described in 2004 as a human pathogen and only one case report has previously been published. We report a case of M. brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long-term multidrug regimen.

AB - Mycobacterium brisbanense is rapid-growing nontuberculous mycobacteria. It was first described in 2004 as a human pathogen and only one case report has previously been published. We report a case of M. brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long-term multidrug regimen.

KW - Adrenal Insufficiency/pathology

KW - Adult

KW - Amikacin/therapeutic use

KW - Anti-Bacterial Agents/therapeutic use

KW - Clarithromycin/therapeutic use

KW - Drug Therapy, Combination

KW - Humans

KW - Male

KW - Moxifloxacin/therapeutic use

KW - Mycobacterium Infections, Nontuberculous/drug therapy

KW - Nontuberculous Mycobacteria/isolation & purification

KW - Respiratory Tract Infections/drug therapy

KW - Sputum/microbiology

U2 - 10.1111/apm.12911

DO - 10.1111/apm.12911

M3 - Journal article

C2 - 30585355

SN - 0903-465X

VL - 127

SP - 106

EP - 108

JO - APMIS. Supplementum

JF - APMIS. Supplementum

IS - 2

ER -