Impact of gain-of-function mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) on glucose and lipid homeostasis

Medicin og biovidenskab

• Animal Models 7%
• Area Under Curve 4%
• Bone and Bones 14%
• Case-Control Studies 3%
• Cholesterol 3%
• Coronary Artery Disease 4%
• Drug Discovery 5%
• Gain of Function Mutation 78%
• Glucose 37%
• Homeostasis 43%
• Hyperlipidemias 4%
• Insulin 6%
• Insulin Resistance 12%
• Insulin Secretion 19%
• Islets of Langerhans 4%
• Lipid Metabolism 14%
• Lipids 38%
• Liver 2%
• Loss of Function Mutation 5%
• Low Density Lipoprotein Receptor-Related Protein-5 100%
• MASS syndrome 8%
• Metabolic Networks and Pathways 4%
• Mutation 13%
• Osteoporosis 4%
• oxidized low density lipoprotein 14%
• Population 1%
• Proton Magnetic Resonance Spectroscopy 5%
• Sample Size 4%
• Serum 4%
• Triglycerides 3%
• Type 2 Diabetes Mellitus 7%