Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
Kathrin Maedler, Joachim Størling, Jeppe Sturis, Richard A Zuellig, Giatgen A Spinas, Per O G Arkhammar, Thomas Mandrup-Poulsen, Marc Y Donath
Dyk ned i forskningsemnerne om 'Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.'. Sammen danner de et unikt fingeraftryk.