Fenfluramine Reduces [¹¹C]Cimbi-36 Binding to the 5-HT_2A Receptor in the Nonhuman Primate Brain

Medicin og biovidenskab

• Cimbi-36 100%
• Fenfluramine 65%
• Receptor, Serotonin, 5-HT2A 61%
• 5-methyl-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromene-2-carboxylic acid (4-morpholin-4-yl-phenyl)amide 48%
• Primates 43%
• volinanserin 39%
• Serotonin 24%
• Brain 22%
• Serotonin Receptor Agonists 15%
• Positron-Emission Tomography 10%
• Receptor, Serotonin, 5-HT1B 8%
• Serotonin Antagonists 7%
• Neocortex 6%
• Macaca mulatta 6%
• Thalamus 5%
• Haplorhini 5%
• Cerebellum 5%
• Neurotransmitter Agents 5%