Excretion of purine base derivatives after intake of bacterial protein meal in pigs

TY - JOUR

T1 - Excretion of purine base derivatives after intake of bacterial protein meal in pigs

AU - Hellwing, Anne Louise Frydendahl

AU - Tauson, Anne-Helene

AU - Skrede, A.

N1 - 10. International Symposium on Digestive Physiology in Pigs, Denmark 2006, Part 2

PY - 2007

Y1 - 2007

N2 - Bacterial protein meal has a high content ofprotein but also of RNA and DNA. Sixteen barrows were allocated to four diets containing increasing levels of bacterial protein meal (BPM), from weaning to 80 kg live weight, to evaluate whether the RNA and DNA contents of BPM influenced the retention of nitrogen. It was hypothesised that an increased intake of RNA and DNA would lead to an increased urinary excretion of purine base derivatives and increased plasma concentrations. Retention of nitrogen was unaffected by dietary content of BPM (P=0.08) and the urinary excretion of purine base derivatives increased with increasing dietary content of BPM. No differences in fasting plasma concentration of uric acid, xanthine and hypoxanthine were observed. It can therefore be concluded that increasing levels of dietary BPM maintained protein accretion and led to changes in excretion of purine detrivatices, but did not cause uricogenic effects in the pigs.

AB - Bacterial protein meal has a high content ofprotein but also of RNA and DNA. Sixteen barrows were allocated to four diets containing increasing levels of bacterial protein meal (BPM), from weaning to 80 kg live weight, to evaluate whether the RNA and DNA contents of BPM influenced the retention of nitrogen. It was hypothesised that an increased intake of RNA and DNA would lead to an increased urinary excretion of purine base derivatives and increased plasma concentrations. Retention of nitrogen was unaffected by dietary content of BPM (P=0.08) and the urinary excretion of purine base derivatives increased with increasing dietary content of BPM. No differences in fasting plasma concentration of uric acid, xanthine and hypoxanthine were observed. It can therefore be concluded that increasing levels of dietary BPM maintained protein accretion and led to changes in excretion of purine detrivatices, but did not cause uricogenic effects in the pigs.

KW - Former LIFE faculty

KW - Purine base derivatives

KW - Pig

KW - Bacterial protein meal

U2 - 10.1016/j.livsci.2007.01.070

DO - 10.1016/j.livsci.2007.01.070

M3 - Journal article

SN - 1871-1413

VL - 109

SP - 70

EP - 72

JO - Livestock Science

JF - Livestock Science

IS - 1-3

ER -