TY - JOUR
T1 - European Union funded project on the development of a whole complement deficiency screening ELISA
T2 - A story of success and an exceptional manager: Mohamed R. Daha
AU - Würzner, Reinhard
AU - Tedesco, Francesco
AU - Garred, Peter
AU - Mollnes, Tom Eirik
AU - Truedsson, Lennart
AU - Turner, Malcolm W
AU - Sommarin, Yngve
AU - Wieslander, Jörgen
AU - Sim, Robert B
N1 - Copyright © 2015 Elsevier Ltd. All rights reserved.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - A whole complement ELISA-based assay kit, primarily designed to screen for deficiencies in components of the complement system was developed during a European Union grant involving more than a dozen European scientists and a small-medium enterprise company (Wieslab, which later merged into Eurodiagnostica). The consortium was led by Prof. Mohamed R. Daha who had already guided a preceding European grant which prepared the ground for this endeavor to create a novel and sophisticated complement measurement tool. The final result of the grant was a scientific publication (Seelen et al., 2005, J. Immunol. Methods 296, 187-198) and a commercially available complement deficiency screening kit, WIESLAB® Complement system Screen. Thereafter, the group decided to carry on with a grant, located at Innsbruck Medical University, and supported by royalties and unrestricted educational grants from Eurodiagnostica, Malmö, entitled "Search for Applications for WIESLAB® Complement system Screen (SAW)" with the aim to look for further applications of this assay. During the latter project the group organized several scientific meetings aimed at evaluating the use of the assay as well as developing further branches of its platform. A look back over almost two decades reveals a great story of excellent research which was also commercially successful, fulfilling the aims of European Union grants. It is also a story of ageless friendship, only possible due to the vision and guidance of an exceptional manager: Moh Daha.
AB - A whole complement ELISA-based assay kit, primarily designed to screen for deficiencies in components of the complement system was developed during a European Union grant involving more than a dozen European scientists and a small-medium enterprise company (Wieslab, which later merged into Eurodiagnostica). The consortium was led by Prof. Mohamed R. Daha who had already guided a preceding European grant which prepared the ground for this endeavor to create a novel and sophisticated complement measurement tool. The final result of the grant was a scientific publication (Seelen et al., 2005, J. Immunol. Methods 296, 187-198) and a commercially available complement deficiency screening kit, WIESLAB® Complement system Screen. Thereafter, the group decided to carry on with a grant, located at Innsbruck Medical University, and supported by royalties and unrestricted educational grants from Eurodiagnostica, Malmö, entitled "Search for Applications for WIESLAB® Complement system Screen (SAW)" with the aim to look for further applications of this assay. During the latter project the group organized several scientific meetings aimed at evaluating the use of the assay as well as developing further branches of its platform. A look back over almost two decades reveals a great story of excellent research which was also commercially successful, fulfilling the aims of European Union grants. It is also a story of ageless friendship, only possible due to the vision and guidance of an exceptional manager: Moh Daha.
KW - Allergy and Immunology
KW - Biomedical Research
KW - Complement System Proteins
KW - Cooperative Behavior
KW - Enzyme-Linked Immunosorbent Assay
KW - European Union
KW - Gene Expression
KW - History, 20th Century
KW - History, 21st Century
KW - Humans
U2 - 10.1016/j.molimm.2015.05.003
DO - 10.1016/j.molimm.2015.05.003
M3 - Journal article
C2 - 26006049
SN - 0161-5890
VL - 68
SP - 63
EP - 66
JO - Molecular Immunology
JF - Molecular Immunology
IS - 1
ER -
