Epidemiological studies of the non-specific effects of vaccines: II--methodological issues in the design and analysis of cohort studies

TY - JOUR

T1 - Epidemiological studies of the non-specific effects of vaccines: II--methodological issues in the design and analysis of cohort studies

AU - Farrington, C P

AU - Firth, M J

AU - Moulton, L H

AU - Ravn, H

AU - Evans, S

AU - Working Group on Non-specific Effects of Vaccines

AU - Andersen, Per Kragh

N1 - Keywords: Bias (Epidemiology); Child, Preschool; Cohort Studies; Forms and Records Control; Humans; Infant; Medical Records; Vaccination; Vaccines

PY - 2009

Y1 - 2009

N2 - We review sources of bias which can affect non-randomized cohort studies of non-specific effects of vaccines on child mortality. Using examples from the literature on non-specific effects, we describe different sources of selection and information bias, and, where possible, outline analysis strategies to mitigate or eliminate such biases.

AB - We review sources of bias which can affect non-randomized cohort studies of non-specific effects of vaccines on child mortality. Using examples from the literature on non-specific effects, we describe different sources of selection and information bias, and, where possible, outline analysis strategies to mitigate or eliminate such biases.

U2 - 10.1111/j.1365-3156.2009.02302.x

DO - 10.1111/j.1365-3156.2009.02302.x

M3 - Journal article

C2 - 19531116

SN - 1360-2276

VL - 14

SP - 977

EP - 985

JO - Tropical Medicine & International Health

JF - Tropical Medicine & International Health

IS - 9

ER -