TY - JOUR
T1 - Dietary reference values for thiamin
T2 - (Scientific Opinion)
AU - Sjödin, Anders Mikael
AU - EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
N1 - EFSA 2016 4653
PY - 2016/12/19
Y1 - 2016/12/19
N2 - Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion–repletion studies in adults on the amount of dietary thiamin intake associated with the erythrocyte transketolase activity coefficient (aETK) < 1.15, generally considered to reflect an adequate thiamin status, or with the restoration of normal (baseline)
erythrocyte transketolase activity, without a sharp increase in urinary thiamin excretion, can be used to estimate thiamin requirement. In the absence of new scientific evidence, the Panel endorses the average requirement (AR) of 0.072 mg/MJ (0.3 mg/1,000 kcal) for all adults proposed by the Scientific Committee for Food (SCF) in 1993 on the basis of one depletion–repletion study, in which both aETK and urinary thiamin excretion were measured. Results from other depletion–repletion studies are in agreement with this value. The Panel agrees on the coefficient of variation of 20% used by the SCF to cover uncertainties related to distribution of thiamin requirements in the general population, and
endorses the population reference intake (PRI) of 0.1 mg/MJ (0.4 mg/1,000 kcal) set by the SCF for all adults. The same AR and PRI as for adults, expressed in mg/MJ, are proposed for infants aged 7–11 months, children aged 1 to < 18 years, and during pregnancy and lactation, under the assumption that the relationship between thiamin requirement and energy requirement is the same in
all population groups.
AB - Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion–repletion studies in adults on the amount of dietary thiamin intake associated with the erythrocyte transketolase activity coefficient (aETK) < 1.15, generally considered to reflect an adequate thiamin status, or with the restoration of normal (baseline)
erythrocyte transketolase activity, without a sharp increase in urinary thiamin excretion, can be used to estimate thiamin requirement. In the absence of new scientific evidence, the Panel endorses the average requirement (AR) of 0.072 mg/MJ (0.3 mg/1,000 kcal) for all adults proposed by the Scientific Committee for Food (SCF) in 1993 on the basis of one depletion–repletion study, in which both aETK and urinary thiamin excretion were measured. Results from other depletion–repletion studies are in agreement with this value. The Panel agrees on the coefficient of variation of 20% used by the SCF to cover uncertainties related to distribution of thiamin requirements in the general population, and
endorses the population reference intake (PRI) of 0.1 mg/MJ (0.4 mg/1,000 kcal) set by the SCF for all adults. The same AR and PRI as for adults, expressed in mg/MJ, are proposed for infants aged 7–11 months, children aged 1 to < 18 years, and during pregnancy and lactation, under the assumption that the relationship between thiamin requirement and energy requirement is the same in
all population groups.
KW - Faculty of Science
KW - Thiamin
KW - Average requirement
KW - Population reference intake
KW - Dietary reference value
U2 - 10.2903/j.efsa.2016.4653
DO - 10.2903/j.efsa.2016.4653
M3 - Journal article
SN - 1831-4732
VL - 14
JO - E F S A Journal
JF - E F S A Journal
IS - 12
M1 - 4653
ER -