Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity

Dora Romaguera; Lars Henrik Ängquist; Huaidong Du; Marianne Uhre Jakobsen; Nita G Forouhi; Jytte Halkjaer; Edith J M Feskens; Daphne L van der A; Giovanna Masala; Annika Steffen; Domenico Palli; Nicholas J Wareham; Kim Overvad; Anne Tjønneland; Heiner Boeing; Elio Riboli; Thorkild I A Sørensen

doi:10.1371/journal.pone.0011588

Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity

Dora Romaguera, Lars Henrik Ängquist, Huaidong Du, Marianne Uhre Jakobsen, Nita G Forouhi, Jytte Halkjaer, Edith J M Feskens, Daphne L van der A, Giovanna Masala, Annika Steffen, Domenico Palli, Nicholas J Wareham, Kim Overvad, Anne Tjønneland, Heiner Boeing, Elio Riboli, Thorkild I A Sørensen

69 Citationer (Scopus)

Abstract

Background: Given the recognized health effects of visceral fat, the understanding of how diet can modulate changes in the phenotype "waist circumference for a given body mass index (WC_BMI)", a proxy measure of visceral adiposity, is deemed necessary. Hence, the objective of the present study was to assess the association between dietary factors and prospective changes in visceral adiposity as measured by changes in the phenotype WC_BMI. Methods and Findings: We analyzed data from 48,631 men and women from 5 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Anthropometric measurements were obtained at baseline and after a median follow-up time of 5.5 years. WC_BMI was defined as the residuals of waist circumference regressed on body mass index, and annual change in WC_BMI (ΔWC_BMI, cm/y) was defined as the difference between residuals at follow-up and baseline, divided by follow-up time. The association between energy, energy density (ED), macronutrients, alcohol, glycemic index (GI), glycemic load (GL), fibre and ΔWC_BMI was modelled using centre-specific adjusted linear regression, and random-effects meta-analyses to obtain pooled estimates. Men and women with higher ED and GI diets showed significant increases in their WC_BMI, compared to those with lower ED and GI [1 kcal/g greater ED predicted a ΔWC_BMI of 0.09 cm (95% CI 0.05 to 0.13) in men and 0.15 cm (95% CI 0.09 to 0.21) in women; 10 units greater GI predicted a ΔWC_BMI of 0.07 cm (95% CI 0.03 to 0.12) in men and 0.06 cm (95% CI 0.03 to 0.10) in women]. Among women, lower fibre intake, higher GL, and higher alcohol consumption also predicted a higher DWC_BMI. Conclusions: Results of this study suggest that a diet with low GI and ED may prevent visceral adiposity, defined as the prospective changes in WC_BMI. Additional effects may be obtained among women of low alcohol, low GL, and high fibre intake.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	5
Udgave nummer	7
Sider (fra-til)	e11588
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0011588 https://doi.org/10.1371/journal.pone.0011588
Status	Udgivet - 1 jan. 2010

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Romaguera, D., Ängquist, L. H., Du, H., Jakobsen, M. U., Forouhi, N. G., Halkjaer, J., Feskens, E. J. M., van der A, D. L., Masala, G., Steffen, A., Palli, D., Wareham, N. J., Overvad, K., Tjønneland, A., Boeing, H., Riboli, E., & Sørensen, T. I. A. (2010). Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity. P L o S One, 5(7), e11588. https://doi.org/10.1371/journal.pone.0011588, https://doi.org/10.1371/journal.pone.0011588

Romaguera, D, Ängquist, LH, Du, H, Jakobsen, MU, Forouhi, NG, Halkjaer, J, Feskens, EJM, van der A, DL, Masala, G, Steffen, A, Palli, D, Wareham, NJ, Overvad, K, Tjønneland, A, Boeing, H, Riboli, E & Sørensen, TIA 2010, 'Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity', P L o S One, bind 5, nr. 7, s. e11588. https://doi.org/10.1371/journal.pone.0011588, https://doi.org/10.1371/journal.pone.0011588

@article{ea9e6344288343c185c96e9f8c042611,

title = "Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity",

abstract = "Background: Given the recognized health effects of visceral fat, the understanding of how diet can modulate changes in the phenotype {"}waist circumference for a given body mass index (WCBMI){"}, a proxy measure of visceral adiposity, is deemed necessary. Hence, the objective of the present study was to assess the association between dietary factors and prospective changes in visceral adiposity as measured by changes in the phenotype WCBMI. Methods and Findings: We analyzed data from 48,631 men and women from 5 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Anthropometric measurements were obtained at baseline and after a median follow-up time of 5.5 years. WCBMI was defined as the residuals of waist circumference regressed on body mass index, and annual change in WCBMI (ΔWCBMI, cm/y) was defined as the difference between residuals at follow-up and baseline, divided by follow-up time. The association between energy, energy density (ED), macronutrients, alcohol, glycemic index (GI), glycemic load (GL), fibre and ΔWCBMI was modelled using centre-specific adjusted linear regression, and random-effects meta-analyses to obtain pooled estimates. Men and women with higher ED and GI diets showed significant increases in their WCBMI, compared to those with lower ED and GI [1 kcal/g greater ED predicted a ΔWCBMI of 0.09 cm (95% CI 0.05 to 0.13) in men and 0.15 cm (95% CI 0.09 to 0.21) in women; 10 units greater GI predicted a ΔWCBMI of 0.07 cm (95% CI 0.03 to 0.12) in men and 0.06 cm (95% CI 0.03 to 0.10) in women]. Among women, lower fibre intake, higher GL, and higher alcohol consumption also predicted a higher DWCBMI. Conclusions: Results of this study suggest that a diet with low GI and ED may prevent visceral adiposity, defined as the prospective changes in WCBMI. Additional effects may be obtained among women of low alcohol, low GL, and high fibre intake.",

author = "Dora Romaguera and {\"A}ngquist, {Lars Henrik} and Huaidong Du and Jakobsen, {Marianne Uhre} and Forouhi, {Nita G} and Jytte Halkjaer and Feskens, {Edith J M} and {van der A}, {Daphne L} and Giovanna Masala and Annika Steffen and Domenico Palli and Wareham, {Nicholas J} and Kim Overvad and Anne Tj{\o}nneland and Heiner Boeing and Elio Riboli and S{\o}rensen, {Thorkild I A}",

year = "2010",

month = jan,

day = "1",

doi = "10.1371/journal.pone.0011588",

language = "English",

volume = "5",

pages = "e11588",

journal = "PLoS Computational Biology",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "7",

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TY - JOUR

T1 - Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity

AU - Romaguera, Dora

AU - Ängquist, Lars Henrik

AU - Du, Huaidong

AU - Jakobsen, Marianne Uhre

AU - Forouhi, Nita G

AU - Halkjaer, Jytte

AU - Feskens, Edith J M

AU - van der A, Daphne L

AU - Masala, Giovanna

AU - Steffen, Annika

AU - Palli, Domenico

AU - Wareham, Nicholas J

AU - Overvad, Kim

AU - Tjønneland, Anne

AU - Boeing, Heiner

AU - Riboli, Elio

AU - Sørensen, Thorkild I A

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Background: Given the recognized health effects of visceral fat, the understanding of how diet can modulate changes in the phenotype "waist circumference for a given body mass index (WCBMI)", a proxy measure of visceral adiposity, is deemed necessary. Hence, the objective of the present study was to assess the association between dietary factors and prospective changes in visceral adiposity as measured by changes in the phenotype WCBMI. Methods and Findings: We analyzed data from 48,631 men and women from 5 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Anthropometric measurements were obtained at baseline and after a median follow-up time of 5.5 years. WCBMI was defined as the residuals of waist circumference regressed on body mass index, and annual change in WCBMI (ΔWCBMI, cm/y) was defined as the difference between residuals at follow-up and baseline, divided by follow-up time. The association between energy, energy density (ED), macronutrients, alcohol, glycemic index (GI), glycemic load (GL), fibre and ΔWCBMI was modelled using centre-specific adjusted linear regression, and random-effects meta-analyses to obtain pooled estimates. Men and women with higher ED and GI diets showed significant increases in their WCBMI, compared to those with lower ED and GI [1 kcal/g greater ED predicted a ΔWCBMI of 0.09 cm (95% CI 0.05 to 0.13) in men and 0.15 cm (95% CI 0.09 to 0.21) in women; 10 units greater GI predicted a ΔWCBMI of 0.07 cm (95% CI 0.03 to 0.12) in men and 0.06 cm (95% CI 0.03 to 0.10) in women]. Among women, lower fibre intake, higher GL, and higher alcohol consumption also predicted a higher DWCBMI. Conclusions: Results of this study suggest that a diet with low GI and ED may prevent visceral adiposity, defined as the prospective changes in WCBMI. Additional effects may be obtained among women of low alcohol, low GL, and high fibre intake.

AB - Background: Given the recognized health effects of visceral fat, the understanding of how diet can modulate changes in the phenotype "waist circumference for a given body mass index (WCBMI)", a proxy measure of visceral adiposity, is deemed necessary. Hence, the objective of the present study was to assess the association between dietary factors and prospective changes in visceral adiposity as measured by changes in the phenotype WCBMI. Methods and Findings: We analyzed data from 48,631 men and women from 5 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Anthropometric measurements were obtained at baseline and after a median follow-up time of 5.5 years. WCBMI was defined as the residuals of waist circumference regressed on body mass index, and annual change in WCBMI (ΔWCBMI, cm/y) was defined as the difference between residuals at follow-up and baseline, divided by follow-up time. The association between energy, energy density (ED), macronutrients, alcohol, glycemic index (GI), glycemic load (GL), fibre and ΔWCBMI was modelled using centre-specific adjusted linear regression, and random-effects meta-analyses to obtain pooled estimates. Men and women with higher ED and GI diets showed significant increases in their WCBMI, compared to those with lower ED and GI [1 kcal/g greater ED predicted a ΔWCBMI of 0.09 cm (95% CI 0.05 to 0.13) in men and 0.15 cm (95% CI 0.09 to 0.21) in women; 10 units greater GI predicted a ΔWCBMI of 0.07 cm (95% CI 0.03 to 0.12) in men and 0.06 cm (95% CI 0.03 to 0.10) in women]. Among women, lower fibre intake, higher GL, and higher alcohol consumption also predicted a higher DWCBMI. Conclusions: Results of this study suggest that a diet with low GI and ED may prevent visceral adiposity, defined as the prospective changes in WCBMI. Additional effects may be obtained among women of low alcohol, low GL, and high fibre intake.

U2 - 10.1371/journal.pone.0011588

DO - 10.1371/journal.pone.0011588

M3 - Journal article

C2 - 20644647

SN - 1932-6203

VL - 5

SP - e11588

JO - PLoS Computational Biology

JF - PLoS Computational Biology

IS - 7

ER -

Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity

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