Dendritic cells in peripheral tolerance and immunity.

TY - JOUR

T1 - Dendritic cells in peripheral tolerance and immunity.

AU - Gad, Monika

AU - Claesson, Mogens Helweg

AU - Pedersen, Anders Elm

N1 - Keywords: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Dendritic Cells; Humans; Immune Tolerance; Immunity, Cellular; Lymphocyte Subsets; Mice

PY - 2003

Y1 - 2003

N2 - Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell-tolerizing and T cell-immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.

AB - Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell-tolerizing and T cell-immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.

M3 - Journal article

C2 - 12974778

SN - 0903-465X

VL - 111

SP - 766

EP - 775

JO - APMIS. Supplementum

JF - APMIS. Supplementum

IS - 7-8

ER -