Data fusion in metabolomic cancer diagnostics

TY - JOUR

T1 - Data fusion in metabolomic cancer diagnostics

AU - Bro, Rasmus

AU - Nielsen, Hans Jørgen

AU - Savorani, Francesco

AU - Kjeldahl, Karin

AU - Christensen, Ib Jarle

AU - Brünner, Nils

AU - Lawaetz, Anders Juul

PY - 2013/2

Y1 - 2013/2

N2 - We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of 1H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.

AB - We have recently shown that fluorescence spectroscopy of plasma samples has promising abilities regarding early detection of colorectal cancer. In the present paper, these results were further developed by combining fluorescence with the biomarkers, CEA and TIMP-1 and traditional metabolomic measurements in the form of 1H NMR spectroscopy. The results indicate that using an extensive profile established by combining such measurements together with the biomarkers is better than using single markers.

U2 - 10.1007/s11306-012-0446-0

DO - 10.1007/s11306-012-0446-0

M3 - Journal article

SN - 1573-3882

VL - 9

SP - 3

EP - 8

JO - Metabolomics

JF - Metabolomics

IS - 1

ER -