Closed-chest-grisemodellen er overlegen ved interventionsstudier af iskæmiperfusionsskade

Sarah Victoria Ekeløf Busch; Natalie Løvland Halladin; Svend Eggert Jensen; Jacob Rosenberg; Ismail Gögenur

Closed-chest-grisemodellen er overlegen ved interventionsstudier af iskæmiperfusionsskade

Sarah Victoria Ekeløf Busch, Natalie Løvland Halladin, Svend Eggert Jensen, Jacob Rosenberg, Ismail Gögenur

6 Citationer (Scopus)

Abstract

Ischaemia reperfusion injury affects the patients' clinical outcomes. An animal model is therefore required in order to test pharmacological interventions and improve the current treatment of acute myocardial infarction (AMI). This review focuses on the endovascular closed-chest porcine model of ischaemia and reperfusion. In contrast to the open-chest porcine model the closed-chest model closely mimics the clinical situation of an AMI and makes it possible to extrapolate the results directly to humans. The model is well suited for future interventional studies.

Bidragets oversatte titel	Closed-chest porcine model is superior in intervention studies of ischaemia reperfusion injury.
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	174
Udgave nummer	26
Sider (fra-til)	1807-1810
Antal sider	4
ISSN	0041-5782
Status	Udgivet - 2012

Citationsformater

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title = "Closed-chest-grisemodellen er overlegen ved interventionsstudier af isk{\ae}miperfusionsskade",

abstract = "Ischaemia reperfusion injury affects the patients' clinical outcomes. An animal model is therefore required in order to test pharmacological interventions and improve the current treatment of acute myocardial infarction (AMI). This review focuses on the endovascular closed-chest porcine model of ischaemia and reperfusion. In contrast to the open-chest porcine model the closed-chest model closely mimics the clinical situation of an AMI and makes it possible to extrapolate the results directly to humans. The model is well suited for future interventional studies.",

author = "Busch, {Sarah Victoria Ekel{\o}f} and Halladin, {Natalie L{\o}vland} and Jensen, {Svend Eggert} and Jacob Rosenberg and Ismail G{\"o}genur",

year = "2012",

language = "Dansk",

volume = "174",

pages = "1807--1810",

journal = "Ugeskrift for Laeger",

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TY - JOUR

T1 - Closed-chest-grisemodellen er overlegen ved interventionsstudier af iskæmiperfusionsskade

AU - Busch, Sarah Victoria Ekeløf

AU - Halladin, Natalie Løvland

AU - Jensen, Svend Eggert

AU - Rosenberg, Jacob

AU - Gögenur, Ismail

PY - 2012

Y1 - 2012

N2 - Ischaemia reperfusion injury affects the patients' clinical outcomes. An animal model is therefore required in order to test pharmacological interventions and improve the current treatment of acute myocardial infarction (AMI). This review focuses on the endovascular closed-chest porcine model of ischaemia and reperfusion. In contrast to the open-chest porcine model the closed-chest model closely mimics the clinical situation of an AMI and makes it possible to extrapolate the results directly to humans. The model is well suited for future interventional studies.

AB - Ischaemia reperfusion injury affects the patients' clinical outcomes. An animal model is therefore required in order to test pharmacological interventions and improve the current treatment of acute myocardial infarction (AMI). This review focuses on the endovascular closed-chest porcine model of ischaemia and reperfusion. In contrast to the open-chest porcine model the closed-chest model closely mimics the clinical situation of an AMI and makes it possible to extrapolate the results directly to humans. The model is well suited for future interventional studies.

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 174

SP - 1807

EP - 1810

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 26

ER -

Closed-chest-grisemodellen er overlegen ved interventionsstudier af iskæmiperfusionsskade

Abstract

Fingeraftryk

Citationsformater